(25) Briefly, [micro]OCT is conducted with a spectral-domain OCT system with a broad bandwidth supercontinuum light source spanning from 650 to 950 nm, which provides an axial resolution
of less than 1 [micro]m in tissue.
'A diagnostic run takes about five minutes and provides images with an axial resolution
of 10pm and a lateral resolution of about 30pm,' explained Tearney.
Limitations include high phototoxicity, insufficient axial resolution
, a need for specialized sample handling devices, and lack of tools for precise compound administration.
While SD-OCT is typically slower than SS-OCT, it offers superior phase stability and axial resolution
, which is beneficial in Doppler flowmetry or capillary imaging that require high phase stability and fine axial resolution
They demonstrated that the axial resolution
was higher in AS-OCT compared to USB and that AS-OCT was superior in visualizing lesions involving the lateral and anterior aspects of the iris.
Fortunately, axial bulk motion noise is rejected by split-spectrum amplitude-decorrelation angiography , which trades some of the axial resolution
for decreased noise and higher transverse resolution .
When testing the axial resolution
, the transducer was adjusted to be perpendicular to the wire phantom, while for lateral resolution testing it will be parallel to the wire phantom, just as Figure 7(a) shows.
, offered by listed devices, is as follows: Pentacam-Scheimpflug camera--10 [micro]m, Visante OCT--18 [micro]m, and Casia OCT--10 [micro]m.
Image resolution is determined by lateral and axial resolution
. Lateral resolution is the same as in widefield microscopy, and is given by the numerical aperture (NA) of the detection objective and the wavelength.
The functionality and potential of time-domain (TD-OCT) machines was limited due to slow scanning speeds of 400 A-Scans per second and an axial resolution
The ability of instrument to distinguish between two structures located very close together along axis of ultrasound beam is called its axial resolution
. The axial resolution
is best when groups of waves emitted have a short wave length.