With the exception of the abortifacient effects in animals, studies have not documented teratogenicity or other fetal harm in animals or humans receiving
interferons. However, the potential for long-term effects in a child exposed to
interferons in utero is unknown.
Headquartered in Cambridge, MA, the company's revenues are generated from international sales of AVONEX (
Interferon beta-1a) for treatment of relapsing forms of multiple sclerosis, and from the worldwide sales by licensees of a number of products, including alpha
interferon and hepatitis B vaccines and diagnostic products.
Research thus far has concentrated on the drugs' enhancement of
interferon and natural killer cell activity, which Carter calls the "fighting couple" of the immune system.
Material and Methods: The study included 15 co-infected patients of hepatitis B and C resistant to
interferon therapy and 15 healthy individuals as control.
pegylated
interferons conventional
interferons alpha2a and 2b along with ribavirin was the 4-6 standard treatment for chronic hepatic C patients.
Identification of genes differentially regulated by
interferon alpha, beta, or gamma using oligonucleotide arrays.
(Santiago, Chile) to distribute Viragen's natural human alpha
interferon, Multiferon, exclusively in Chile.
Patients and Methods: The study after approved by institute's ethics committee was conducted on 15 HCV infected patients who were non responder to
interferon therapy and 5 controls responder to
interferon therapy.
We have demonstrated that the nonstructural protein 1 (NS1) of influenza viruses has
interferon antagonist activity (16).
Although
interferons are proteins and are probably digested if taken orally, it's best to avoid them during nursing because of the potential for serious toxicity in the infant.
My wife has just been prescribed
interferon for her Multiple Sclerosis.What do I need to know about it?
They are representative compounds from major antiviral pharmacologic classes that are currently commercially available: nucleoside analogs,
interferons, protease inhibitors, reverse transcriptase inhibitors and neuraminidase inhibitors.