Medical

CLEC2D

A gene on chromosome 12p13 that encodes the receptor for KLRB1, which binds high-molecular-weight sulfated glycosaminoglycans and protects target cells against natural killer cell-mediated lysis. CLEC2D inhibits osteoclast formation, and by extension, bone resorption, and modulates the release of interferon-gamma.

References in periodicals archive

In this regard, 14 genes involved in NK activity were modulated in NCGS samples (i.e., LILRA1, LILRA2, CLEC2D, and KLRC4).

Immune Response to Rotavirus and Gluten Sensitivity

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