ca·ten·in

(ka-tēn'in),

Cytoplasmic molecule that serves as a link between cadherins and the cytoskeleton of cells, allowing the formation of adherent junctions. There are two types: β-catenin, which is linked to the cadherin itself and α-catenin, which associates with actin microfilaments.

[L. catena, chain, + -in]

Farlex Partner Medical Dictionary © Farlex 2012

JUP

A gene on chromosome 17q21 that encodes a major cytoplasmic protein common to both submembranous plaques of desmosomes and intermediate junctions. JUP forms distinct complexes with cadherins, belongs to the catenin family and contains a distinct amino acid motif known as armadillo repeat.

Molecular pathology
JUP mutations are associated with Naxos disease.

ca·ten·in

(kă-tē'nin)

Cytoplasmic molecule that serves as a link between cadherins and the cytoskeleton of cells, allowing the formation of adherent junctions. There are two types: beta-catenin, which is linked to the cadherin itself, and alpha-catenin, which associates with actin microfilaments.

[L. catena, chain, + -in]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

catenin

a PROTEIN initially characterized because of its association with the ACTIN of the CYTOSKELETON, where it acts as a bridging protein between CADHERIN and actin.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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References in periodicals archive

The sections were stained for the following markers: Pancytokeratin (Leica Bond AE1/AE3), NSE (Leica Bond 22C9), CD56 (Leica Bond CD564), Vimentin (Leica Bond V9), CD10 (Leica Bond 56C6), progesterone receptor (Leica Bond 16), [beta] catenin (Leica Bond 17C2), chromogranin (VENTANA), synaptophysin (Leica) and CD99 (VENTANA O13).

CLINICOPATHOLOGICAL STUDY OF SOLID PSEUDOPAPILLARY TUMOR OF PANCREAS

The [alpha], [beta], p, and [gamma] catenins play important roles in intercellular signal transduction.

Categorization of insitu breast carcinoma based on morphology and immunohistochemistry

The amounts of CD31, VE cadherin, and [beta] catenin in celllysate and VEGF, E-selectin, MMP 9, and MMP 2 in medium were quantitated by ELISA.

Inhibition of angiogenesis in vitro by chebulagic acid: a COX-LOX dual inhibitor

This paper shows for the first time the TH effect on the distribution and expression of cadherin and catenin cell adhesion molecules in the B.

Expression of cell adhesion molecules in the normal and T3 blocked development of the tadpole's kidney of Bufo arenarum (Amphibian, Anuran, Bufonidae)/ Expressao das moleculas de adesao celular no desenvolvimento normal e com a inibicao do hormonio tireoidea do rim nas larvas do Bufo arenarum (Amphibia, Anura, Bufonidae)

These studies suggested that cadherin and catenin alterations cause deformation of the synapse and can affect long-term plasticity.

Effects of [beta]-catenin on dendritic morphology and simulated firing patterns in cultured hippocampal neurons

The scientists, led by Dr Eric Adams, have found a gene called catenin is altered in nearly all cases studied.

Scientists expose baby cancer gene

Medical experts claim the miracle chemical beta catenin could be used to "reprogramme" hairless adult skin to grow new folicles.

We're baldly going where no baldies have gone before; IRISHMEN READY FOR HAIR-LOSS CURE

The merged image is an overlay of the DAPI and catenin images (scale bar = 50 [micro]m, mean [+ or -] SD, n = 3, ** p < 001).

Intracellular Calcium Determines the Adipogenic Differentiation Potential of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells via the Wnt5a/[beta]-Catenin Signaling Pathway

Nuclear accumulation of [beta] catenin is seen in squamoid areas ((f), x400).

Two Cases of Sinonasal Non-Intestinal-Type Adenocarcinoma with Squamoid Morules Expressing Nuclear [beta]-Catenin and CDX2: A Curious Morphologic Finding Supported by Molecular Analysis

Phosphorylation of AKT/PKB by CK2 is necessary for the AKT dependent up regulation of [beta] catenin transcriptional activity.

CASEIN KINASE 2 AND SURVIVIN MODULATION IN PROSTATE AND BREAST CANCER

As to noncanonical Wnt signaling components being expressed in primary neurons as a consequence of Wnt3a treatment, we intersected the 170 nominally differentially expressed genes with the reactome pathway "beta catenin independent Wnt signaling" including 143 genes belonging to PCP and/or [Ca.sup.2+] noncanonical pathways (DOI: 10.3180/REACT_172694.1).

Early Transcriptional Changes Induced by Wnt/[beta]-Catenin Signaling in Hippocampal Neurons