The relative mRNA expression levels of genes (DKK-1,
beta-catenin, c-myc, cyclin D1, and survivin) were normalized to GAPDH, calculated by using the [2.sup.-[DELTA][DELTA]Ct] method.
Kaykas, "WNT and
beta-catenin signalling: diseases and therapies," Nature Reviews.
Biotin-rich, optically clear nuclei express estrogen receptor-beta: tumors with morules may develop under the influence of estrogen and aberrant
beta-catenin expression.
Thus,
beta-catenin, GSK-3beta, and the ratio of phosphorylated/dephosphorylated GSK-3beta were detected to determine whether inhibiting the Wnt/beta-catenin signaling pathway is the key to induce MSCs differentiation into cardiomyocytes.
The microphthalmia-associated transcription factor Mitf interacts with
beta-catenin to determine target gene expression.
Nuclear
beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions.
Expression of epithelial-cadherin, alpha-catenin and
beta-catenin during human intrahepatic bile duct development: a possible role in bile duct morphogenesis.
Our data suggest that the broad spectrum of pharmacological action of Uncaria tomentosa involves inhibition of the Wnt-signaling pathway, downstream of
beta-Catenin activity.
Beta-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarction.
Frecuent mutations of
beta-catenin in mouse colon tumors induces by azoxymethane.
Biphenotypic sinonasal sarcoma: an expanded immunoprofile including consistent nuclear
beta-catenin positivity and absence of SOX10 expression.