Uniform size, symmetrical periarticular distribution with a normal bone scan or slightly increased activity, normal alkaline and acid phosphatase help to differentiate
osteopoikilosis from osteoblastic metastasis where there is asymmetry, axial skeleton involvement, bony destruction, and positive bone scan.
Osteopoikilosis has numerous round to ovoid white densities of similar size spread throughout all bones; approximately 10% of
osteopoikilosis is accompanied by skin elastic or collagen nevi, named as BOS.
Osteopoikilosis: a radiological and pathological study.
From his personal history, we discovered an incipient bilateral coxarthrosis, lumbar discopathy and an observation of
osteopoikilosis, diagnosis which was suspected after a MRI a month before presentation.
Osteopoikilosis (also called spotted bone) is a benign, possibly autosomal dominant dysplasia of bones, occurring in 1 per 50,000 people.
Osteopoikilosis can be diagnosed using a plain radiograph through the identification of multiple, variably shaped and sized radio-opaque spots clustered around joints and scattered throughout the skeleton.
To our knowledge, DXA scan has not yet been reported in
osteopoikilosis disease.
Osteopoikilosis is an autosomal dominant sclerosing bone dysplasia that results in focal deposits of thickened lamellar bone in the spongiosa.
It may occur in association with other types of sclerosing bone dysplasias such as
osteopoikilosis and osteopathia striata (4) and with tumor-forming disease such as tuberous sclerosis and neurofibromatosis.
Osteopoikilosis, also called "spotted bone disease," is a rare, benign, autosomal dominant disorder.
The radiological differential diagnosis include
osteopoikilosis, osteopetrosis, arthrogryposis multiplex congenita, and osteopathia striata (11).
Osteopoikilosis (osteopathia condensans disseminata) is a rare sclerosing bone dysplasia of unknown etiology.