glomerulosclerosis
[glo-mer″u-lo-sklĕ-ro´sis] diabetic glomerulosclerosis (
intercapillary glomerulosclerosis) a degenerative complication of
diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson)
lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called
Kimmelstiel-Wilson syndrome.
focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the
nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also
focal glomerular sclerosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.