Posttranslational modification of E-cadherin by core fucosylation regulates Src activation and induces epithelial-mesenchymal transition-like process in lung cancer cells.
Xu, "Regulating the activity of class II transactivator by
posttranslational modifications: exploring the possibilities," Molecular and Cellular Biology, vol.
Seto, "Lysine acetylation: codified crosstalk with other
posttranslational modifications," Molecular Cell, vol.
Cheema, "Small changes huge impact: the role of protein
posttranslational modifications in cellular homeostasis and disease," Journal of Amino Acids, vol.
Additional potential
posttranslational modifications that could affect LDH were then investigated to determine if there was an alternate regulatory mechanism that could be responsible for suppressing LDH activity during anoxia.
Among the epigenome which is defined by DNA methylation patterns and the associated
posttranslational modifications of histories and non histone proteins is the key regulatory circuit (2).
BuzHs, "Citrullination: a
posttranslational modification in health and disease," International Journal of Biochemistry and Cell Biology, vol.
It is also suggested that most of the regulators of biological clock (per, cry genes/gene products) undergo
posttranslational modification especially phosphorylation by casein kinase I (CK-I) and Dexras1 has been shown to have phosphorylation site for CK-I [58].
(iii) Recently, another approach has been developed called PROTOMAP (Protein Topography and Migration Analysis Platform) which combines Sodium Dodecyl Sulphate Poly Acrylamide Gel Electrophoresis (SDSPAGE) with shotgun proteomics to enable detection of changes in gel migration such as those caused by proteolysis or
posttranslational modification [11].
WALSH, C., 2006,
Posttranslational modification of proteins: Expanding nature's inventory.