phos·pho·trans·fer·as·es

(fos'fō-trans'fĕr-ās-ĕz),

A subclass of transferases (EC subclass 2.7) transferring phosphorus-containing groups. Phosphotransferases include the "kinases" (2.7.1) transferring phosphate to alcohols, to carboxyl groups (2.7.2), to nitrogenous groups (2.7.3), or to another phosphate group (2.7.4). Phosphomutases (5.4.2) catalyze apparent intramolecular transfers; pyrophosphokinases (2.7.6) catalyze transfer of the pyrophosphate group; nucleotidyltransferases (2.7.7) catalyze transfer of the nucleotide (nucleotidyl) groups (including polyribonucleotide nucleotidyltransferase) and other similar groups (2.7.8).

Synonym(s): transphosphatases

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References in periodicals archive

The second most common types of AME were phosphotransferases, followed by nucleotidyltransferases in which aph(3)-IV and ant(3)-I were detected among 50% (33/66) and 44% (29/66) of isolates, respectively.

Molecular Identification of Aminoglycoside-Modifying Enzymes and Plasmid-Mediated Quinolone Resistance Genes among Klebsiella pneumoniae Clinical Isolates Recovered from Egyptian Patients

Domain search results through SMART program (http://smart.embl-heidelberg.de) confirmed that the horse CK-M domain function is related SMART to enzyme adenosine triphosphate guanido phosphotransferases. Phylogenetic analysis of the equine CK-M gene with the Neighbor-Joining method showed that the pig and the rodent were, respectively, the closest and the furthest species (Figure 2).

Molecular characterization and expression analysis of creatine kinase muscle (CK-M) gene in horse

In the final steps, the CDP-choline and the CDP-ethanolamine derivatives are condensed with diacylglycerol, catalysed by multiple DAG-choline and DAG-ethanolamine phosphotransferases (CPT, EPT, CEPT), to release CDP and to produce the bilayer forming phospholipids PC and PE at the endoplasmic reticulum (ER).

Formation and regulation of mitochondrial membranes

Miziorko, "Identification of active site residues in mevalonate diphosphate decarboxylase: implications for a family of phosphotransferases," Protein Science, vol.

Binding stoichiometry of a recombinant selenophosphate synthetase with one synonymic substitution E197D to a fluorescent nucleotide analog of ATP, TNP-ATP

aminoglycoside acetyltransferases (AACs), aminoglycoside nucleotidyltransferases (ANTs), and aminoglycoside phosphotransferases (APHs), each of which will chemically convert one or more substituents of the aminoglycosides (Fig.

An Overview of Strategies for Synthetic Modifications of Aminoglycosides