alanine transaminase

[al´ah-nēn trans-am´ĭ-nās]

an enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. Normally present in many tissues and body fluids, especially in the liver, it is released into the serum as a result of tissue injury; the serum concentration is increased particularly when there is acute damage to hepatic cells, as in viral or toxic hepatitis, infectious mononucleosis, and obstructive jaundice. Called also alanine aminotransferase and glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās),

An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction.

Synonym(s): alanine transaminase, glutamic-pyruvic transaminase, serum glutamic:pyruvic transaminase

Farlex Partner Medical Dictionary © Farlex 2012

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)

An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)

alanine transaminase.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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References in periodicals archive

Characteristic Mean [+ or -] SD Age (y) 26.4 [+ or -] 5 Body mass index (kg [m.sup.-2]) 25.9 [+ or -] 3 Plasma glucose (mg [dL.sup.-1]) 88.0 [+ or -] 9 Total cholesterol (mg [dL.sup.-1]) 148.9 [+ or -] 29 Triglycerides (mg [dL.sup.-1]) 117.9 [+ or -] 69 High-density lipoprotein cholesterol 34.1 [+ or -] 6 (mg [dL.sup.-1]) Low-density lipoprotein cholesterol 92.3 [+ or -] 27 (mg [dL.sup.-1]) Urea (mg [dL.sup.-1]) 29.3 [+ or -] 7 Uric acid (mg [dL.sup.-1]) 5.0 [+ or -] 1 Glutamic-oxaloacetic transaminase (U [L.sup.-1]) 31.1 [+ or -] 11 Glutamic-pyruvic transaminase (U [L.sup.-1]) 32.4 [+ or -] 11 Systolic Blood Pressure (mmHg) 117.5 [+ or -] 5 Diastolic Blood Pressure (mmHg) 79.3 [+ or -] 6 Data are mean [+ or -] SD.

Inflammatory response after session of resistance exercises in untrained volunteers/Resposta inflamatoria apos sessao de exercicios resistidos em voluntarios destreinados

Revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, and lactic acid dehydrogenase.

Protective efficacy of alpha-lipoic acid against aflatoxinB1-induced oxidative damage in the liver

The concentrations of total cholesterol (Total-C) and the activities of glutamicoxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) in serum were measured according to the colorimetric method using a cholesterol diagnostic-kit (Cholesterol E kit, Asan Pharmaceutical, Korea) and a GOT-GPT assay kit (GOP-GPT assay kit, Asan Pharmaceutical, Korea), respectively.

Comparison of growth performance, carcass characteristics and meat quality of Korean local chickens and silky fowl

Glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), total cholesterol, HDL cholesterol and LDL cholesterol in blood were analyzed according to AOAC (1995).

Evaluation of anti-SE bacteriophage as feed additives to prevent Salmonella enteritidis (SE) in broiler

The activities of glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) in the serum were measured according to the colorimetric method using a GOT-GPT assay kit (GOT-GPT assay kit, Asan Pharmaceutical, Hwaseong-si, Korea).

The dietary effects of fermented chlorella vulgaris (CBT[R]) on production performance, liver lipids and intestinal microflora in laying hens

The blood samples that were collected without anticoagulant were centrifuged at 1,000xg for 20 min at 4[degrees]C and the serum were partitioned into aliquots and stored at -20[degrees]C until analyzed for albumin, glucose, blood urea nitrogen (BUN), calcium, creatinine, glutamic-pyruvic transaminase (GPT), glutamic-oxaloacetic transaminase (GOT), and globulin with a serum analyzer (Hitachi Chemistry Analyzer 7180, Japan).

Effect of dietary supplementation of glutathione on blood biochemical changes and growth performances of Holstein calves

(2) TC = Total cholesterol; GOT = Glutamic-oxaloacetic transaminase; GPT = Glutamic-pyruvic transaminase; BUN = Blood urea nitrogen.

Effects of multiple enzyme (ROVABIO[R] Max) containing carbohydrolases and phytase on growth performance and intestinal viscosity in broiler chicks fed corn-wheat-soybean meal based diets

The concentration of total cholesterol and high density lipoprotein-cholesterol (HDL-C), the activity of glutamicoxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) were estimated according to the colorimetric method using cholesterol diagnostic kit (Cholesterol E kit, HDL-cholesterol kit, Youngdong Medical Corperation) and GOT-GPT assay kit (BCS GOT GPT assay kit, Bio Clinical System Corporation), following the manufacturer's direction.

Effects of dietary skullcap (Scutellaria baicalensis) extract on laying performance and lipid oxidation of chicken eggs

The concentration of total cholesterol (Total-C) and high-density lipoprotein cholesterol (HDL-C), the activity of glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) in serum were measured according to the colorimetric method using cholesterol diagnostic-kit (Cholesterol E kit and HDL-cholesterol kit, Youngdong Medical Corporation) and GOT-GPT assay kit (GOT-GPT assay kit, Youngdong Medical Corporation).

Growth performance and antibody response of broiler chicks fed yeast derived [beta]-glucan and single-strain probiotics