Medical

estrone

Also found in: Dictionary, Encyclopedia, Wikipedia.

estrone

 [es´trōn]
an estrogen isolated from pregnancy urine, the human placenta, and palm kernel oil, and also prepared synthetically; used in estrogen replacement therapy for hypogonadism, ovariectomy, primary ovarian failure, atrophic vaginitis, vasomotor menopausal symptoms such as hot flashes, and vulvar atrophy, and in the treatment of dysfunctional uterine bleeding and advanced prostate cancer. Administered intramuscularly or intravaginally. See also conjugated estrogens and esterified estrogens.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

es·trone (E1),

(es'trōn),
A metabolite of 17β-estradiol, commonly found in urine, ovaries, and placenta; has considerably less biologic activity than the parent hormone.
Synonym(s): follicular hormone, folliculin, ketohydroxyestrin, oestrone
Farlex Partner Medical Dictionary © Farlex 2012

estrone

(ĕs′trōn′)
n.
An estrogenic hormone, C18H22O2, that is secreted by the ovaries and by fatty tissue. It is the main form of estrogen in postmenopausal women.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

estrone

E1 An estrogen with very low biologic activity that is the major source of estrogen in children and postmenopausal ♀ ↑ in pregnancy, postmenopausal, ↑ age, obesity, luteal phase of menstrual cycle ↓ in hypogonadism. See Androstendione.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

es·trone

(es'trōn)
A metabolite of 17β-estradiol, commonly found in urine, ovaries, and placenta, with considerably less biologic activity than the parent hormone.
Synonym(s): oestrone.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Mentioned in
References in periodicals archive
The three major naturally occurring forms of oestrogens which are found in human urine are 17[beta]-estradiol (E2) and its principal metabolites, estrone (E1) and estriol (E3).
Assessment of Pharmaceuticals, Personal Care Products, and Hormones in Wastewater Treatment Plants Receiving Inflows from Health Facilities in North West Province, South Africa
Later calli were transferred to MS medium containing 17[beta]-estradiol, estrone, progesterone and androsterone with four different doses (0, 10-4 m mol L-1 and 10-8 m mol L-1 and 10-12 m mol L-1) for 50 days and subcultured in 30 days.
MAMMALIAN SEX HORMONES AFFECT REGENERATION CAPACITY AND ENZYMES ACTIVITY OF TRITICALE (X TRITICOSECALE WITTMACK) IN VITRO CULTURE
[E.sub.1] estrone; [E.sub.2]: estradiol; [E.sub.3]: estriol; 2-[OHE.sub.1]: 2-hydroxyestrone; 2-[OHE.sub.2]: 2-hydroxyestradiol; 16a-[OHE.sub.1] 16a-hydroxyestrone; chlormycetin.
Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry
The wavelength used to detect the estrogens: estrone (E1), 17[beta] estradiol (E2), 17[alpha] ethinylestradiol (EE2) was 280 nm, while the progesterone (Pg) was detected at 241 nm.
Occurrence of female sexual hormones in the Iguazu river basin, Curitiba, Parana State, Brazil/Ocorrencia de hormonios sexuais femininos na bacia do Rio Iguacu, Curitiba, Estado do Parana, Brasil
In this study, compound 3 was synthesized by the reaction of 4-nitrobenzoyl azide with estrone in presence of dimethyl sulfoxide at mild conditions.
Design and synthesis of an indole-estrogen derivative
It has been shown that most estrogen in postmenopausal women is produced in peripheral adipose tissue by aromatization of androstenedione to estrone [7, 35], especially in obese and overweight women.
Effects of obesity on bone mass and quality in ovariectomized female Zucker rats
Comparing biological effects and potencies of estrone and 17 (3-estradiol in mature fathead minnows, Pimephales promelas.
Impacts of sewage waste water on feminization and vitellogenin expression in male fathead minnows
Summary: A simple salting-out assisted liquid-liquid extraction (SALLE) method with acetonitrile combined with high-performance liquid-chromatography was developed and applied for the determination four kinds of estrogens (estradiol (bE2), diethylstilbestrol (DES), estrone (E1) and progesterone (PES)) in milk.
Determination of Estrogens in Milk by HPLC using Salting-Out Extraction
The term "estrogen" includes a group of chemically similar hormones: estrone, estradiol (the most abundant in women of reproductive age) and estriol.
Estrogen
Keywords: Oestrogen, Estrone (E1), Estrone sulfate (E1S), Estradiol (E2), Oestrogen receptor (ER), Aromatase (AROM), Aromatase inhibitors (AIs), Steroid sulfatase (STS), 667 COUMATE (STX64), Dual-aromatase-sulfatase inhibitors (DASI).
Steroid sulfatase inhibitors: promising new therapy for breast cancer
Levels of E1S in blood are 5-10-fold higher than that of unconjugated estrogens, estrone (E1), estradiol (E2), and estriol (E3).
The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.