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androstenedione

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androstenedione

 [an″dro-stēn´de-ōn]
an androgen, C19H30O2, less potent than testosterone, secreted by the testis, ovary, and adrenal cortex.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

an·dro·stene·di·one

(an'drō-stēn'dī-ōn),
Androstanedione with a double bond between C-4 and C-5; an androgenic steroid of weaker biologic potency than testosterone; secreted by the testis, ovary, and adrenal cortex.
Farlex Partner Medical Dictionary © Farlex 2012

androstenedione

(ăn′drə-stēn′dī′ōn)
n.
An unsaturated androgenic steroid, C19H26O2, that is secreted by the testis, ovary, and adrenal cortex and is a precursor of both androgens and estrogens. Until 2005, when its nonprescription sale and use became illegal in the United States, synthetic androstenedione was used as a dietary supplement to enhance athletic performance.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

androstenedione

An androgenic steroid less potent than testosterone, which is produced by the adrenal cortex, ovary and testis and converted to estrone in fat and the liver; in men, overproduction of androstendione may cause feminisation.
 
Increased in
Cushing syndrome; ovarian, testicular or adrenocortical tumours; adrenal hyperplasia; polycystic ovary disease.

Decreased in
Hypogonadism, Addison’s disease.
 
Specimen
Serum.
 
Ref range
Women (premenopausal)—0.5–3 ng/mL; women (postmenopausal)—0.3-8 ng/mL; men—0.9–1.7 ng/mL.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

androstenedione

An androgenic steroid, less potent than testosterone, which is produced by the adrenal cortex and gonads, and converted to estrone in fat and the liver; in ♂, overproduction of androstendione may cause feminization; androstenedione is ↑ in Cushing syndrome, ovarian, testicular, or adrenocortical tumors, adrenal hyperplasia, polycystic ovary disease; it is ↓ in hypogonadism, Addison's disease
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

an·dro·stene·di·one

(an'drō-stēn'dī-ōn)
An androgenic steroid of weaker biologic potency than testosterone; secreted by the testis, ovary, and the cortex of the suprarenal gland.
See also: performance enhancing drug
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Androstenedione

Also called "andro," this hormone occurs naturally during the making of testosterone and estrogen.
Mentioned in: Anabolic Steroid Use
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about androstenedione

Q. What is the difference between ADD and ADHD? My Son has been diagnosed with ADD. Is this the same as ADHD?

A. Here is the general description:
ADHD: Think of these types of children as the energizer bunnies in constant motion. They tend to move about excessively, fidgeting and squirming, and always into things. Remaining seated when expected to is often an impossible task.
ADD: Children with predominately inattentive behaviors, more commonly referred to as ADD, may act very differently. These are the “daydreamers.” They may appear spacey, forgetful, and distracted. They move from one activity to the next, never quite able to complete a task. Often times they begin a task without waiting for the directions and end up frustrated and uncertain. They may seem rather messy, careless and disorganized.

Q. Is there any connection between ADD and Autism? I refer to ADD, not ADHD

A. there is a theory that ADD and learning disabilities are a "continuum" up to Asperger syndrome and autism. due to similarities in brain function and symptoms. mind you- it's a theory.

Q. What is the difference between ADD and ADHD? I know that H stands for hyperactivity, but what does it mean by symptoms? does It have the same treatment?

A. They differ by ADHD kids tend to move around all the time (not like ADD who can sit but not listen), and they are more then careless. They tend to injure themselves over childhood. <br>I saw a nice video that explains about those disorders! <br><object width='425' height='355' id='FiveminPlayer'><param name='allowfullscreen' value='true'/><param name='movie' value='http://www.5min.com/Embeded/5538/'/><embed src='http://www.5min.com/Embeded/5538/' type='application/x-shockwave-flash' width='425' height='355' allowfullscreen='true'></embed></object>
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References in periodicals archive
In this study, significant differences were seen in BMI, waist circumference, waist-hip ratio, parameters indicating hyperandrogenism (Ferriman-Gallwey score, testosterone, and androstenedione levels), parameters indicating insulin resistance (deranged oral glucose tolerance test, fasting insu lin, and HOMA-IR), derangements in lipid profile (LDL, HDL, cholesterol, and triglyceride levels), ovarian reserve parameters (AMH, AFC, and ovarian volume), LH levels, and LH-FSH ratio amongst the clomiphene resistant and sensitive groups.
The concentrations of DHEA, androstenedione, and free testosterone increased with age starting from the age of 6 years [Table 2], [Figure 1].{Table 2}{Figure 1}
Adrenal-derived DHEA-S and DHEA is converted by 3[beta]-hydroxysteroid dehydrogenase (3[beta]-HSD) into androstenedione and testosterone --the latter being the downstream metabolite of androstenediol produced from DHEA via I7[beta]-HSD Type V, which is in close proximity to 3[beta]-HSD In the prostate epithelium.
Crabtree et al., "Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione," The Journal of Clinical Endocrinology and Metabolism, vol.
Concentrations of cortisol, cortisone, DHEA, and androstenedione were measured in cord blood samples using LC-MS/MS (Yamashita et al.
As the gene product of CYP19, aromatase can act on androstenedione generated from the adrenal cortex of adipose tissues to form estrone and testos terone in ovarian tissues to produce androstenedione, and then transform a part of androstenedione into estrone.15,16 Theoretically, LE may be superior to CC because it has no peripheral anti-estrogen effect.
In the trial, the inhibitory potency of saw palmetto supercritical CO2 extract (SPSE) was compared to that of finasteride, an approved 5[alpha]-reductase inhibitor, on the basis of the enzymatic conversion of the substrate androstenedione to the 5[alpha]-reduced product 5[alpha]-androstanedione.
Given their known diurnal rhythms, expected significant differences between groups were found for Cortisol, the cortisolxortisone ratio, corticosterone, dehydroepiandrosterone, and androstenedione.
Effect of finasteride on serum androstenedione and risk of prostate cancer within the Prostate Cancer Prevention Trial: differential effect on high- and low-grade disease.
The main hormone produced from 17[alpha]-hidroxiprogesterone is androstenedione, which can be converted to testosterone by the isoenzyme 17[beta]-hidroxisteroide deidrogenase (HSD17B) in theca cells or to estrone by aromatase (CYP19A1) in granulosa cells.
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