* designating a
cytotoxic drug administration area, which only permits entry to authorised people.
"HPAPIs and
Cytotoxic Drugs Manufacturing Market, (2nd Edition), 2016-2026." March 9, 2016.
He also will oversee the company's potent and
cytotoxic drug development services, which include a dedicated and segregated potent facility.
Cascone previously served as director of potent pharmaceutical development, managing the company's potent and
cytotoxic drug handling capabilities as well as its dedicated and segregated potent facility.
He previously served as director of potent pharmaceutical development, managing Metrics' potent and
cytotoxic drug handling capabilities as well as its dedicated and segregated potent facility.
The SNAP platform offers a simple, chemically-driven approach for linking any anti-cancer antibody with small molecule
cytotoxic drug to deliver ADCs with maximised and uniform ratios of drug to antibody.
GRN1005 is the firm's lead LRP-directed peptide-drug conjugate (LRP-directed PDC) that consists of the
cytotoxic drug, paclitaxel, linked to a peptide (Angiopep-2) that targets the LRP receptor to cross the blood-brain barrier (BBB) and to target tumours in the brain.
This increased survival rate is relevant compared to the 54.5% rate observed in patients with the current standard of care (usually transarterial chemoembolisation with a
cytotoxic drug).
It is only recently that ADC's true potentials were fully tapped, thanks to the significant advances in linker engineering, conjugation technologies and continuous development of highly potent
cytotoxic drugs.
Antibody Fragment-Drug Conjugates (FDCs, also called immuno-conjugates) combine the pharmacological potency of highly
cytotoxic drugs with the high specificity of an antibody against tumour-associated targets.
Based on drug types, global anticancer drugs market is segmented into
cytotoxic drugs, targeted drugs, and hormonal drugs.