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ceruloplasmin

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ceruloplasmin

 [sĕ-roo″lo-plaz´min]
an alpha2-globulin of the plasma, being the form in which most of the plasma copper is transported.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ce·ru·lo·plas·min

(sĕ-rū'lō-plaz'min), [MIM*117700]
A blue, copper-containing α-globulin of blood plasma, with a molecular weight of about 122,000 and 6 or 7 atoms of copper per molecule; involved in copper transport and regulation, and can reduce O2 directly without known intermediates; has ferroxidase and polyamine oxidase activities. Ceruloplasmin is absent in congenital Wilson disease.
[L. caeruleus, dark blue]
Farlex Partner Medical Dictionary © Farlex 2012

ceruloplasmin

(sə-ro͞o′lō-plăz′mĭn)
n.
A blood glycoprotein to which copper is bound during transport and storage.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ceruloplasmin

Ferroxidase Clinical chemistry A dehydrogenase produced in the liver involved in copper detoxification and possibly in mopping up excess oxygen radicals or superoxide anions ↑ in Neoplasms, inflammation, liver disease, rheumatoid arthritis, SLE, pregnancy, OCs, estrogen therapy ↓ in Wilson's disease, Menkes' kinky hair syndrome, hepatitis, cirrhosis, nephrotic syndrome, sprue, scleroderma of small intestine. See Copper.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ce·ru·lo·plas·min

(sĕ-rū'lō-plaz'min)
A blue, copper-containing alpha-globulin of blood plasma; involved in copper transport and regulation, and can reduce O2 directly without known intermediates. Ceruloplasmin is absent in congenital Wilson disease.
[L. caeruleus, dark blue]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Ceruloplasmin

A protein circulating in the bloodstream that binds with copper and transports it.
Mentioned in: Wilson Disease
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
Mentioned in
References in periodicals archive
The present study showed an insignificant decrease in mean ceruloplasmin levels in GDM subjects.
A comparative study of oxidative stress among gestational diabetics and normal pregnancy
Plasma total protein levels (g l-1) were 34.7+-1.77 and 34.9+-1.68, plasma albumin levels (g l-1) were 12.1+-0.82 and 12.8+-0.83 and plasma ceruloplasmin levels (mg dl-1) were 8.56+-0.74 and 9.63+-0.55 for exposure and control groups, respectively.
ALTERATIONS IN HEMATOLOGICAL, IMMUNOLOGICAL AND BIOCHEMICAL PARAMETERS OF TENCH, TINCA TINCA AFTER ACUTE ZINC EXPOSURE
In addition, levels of ceruloplasmin, which is an acute phase reactant, were also observed to be elevated, which is paralleled with the BMI increase.
Evaluation of Oxidative Stress and Thiol-Disulfide Parameters According to the Body Mass Index in Adult Individuals
In the control group, plasma copper was positively correlated not only with HDL-c ([r.sub.s] = 0.479, p = 0.015) but also with serum ceruloplasmin ([r.sub.s] = 0.646, p < 0.001), TC ([r.sub.s] = 0.446, p = 0.025), and LDL-c ([r.sub.s] = 0.445, p = 0.029).
Association of Copper Status with Lipid Profile and Functional Status in Patients with Amyotrophic Lateral Sclerosis
Caption: Figure 5: Intravitreal level of (a) APOA2 and (b) ceruloplasmin measured by ELISA.
Difference in the Vitreal Protein Profiles of Patients with Proliferative Diabetic Retinopathy with and without Intravitreal Conbercept Injection
Keywords: Wilson's; Hepatolenticular degeneration; Copper; Cerebellar; Hepatic; Kayser fleisher rings; ATP7B; Ceruloplasmin
Suspected Wilson's disease presenting with normal serum ceruloplasmin levels
bound to ceruloplasmin and 7% is loosely bound to albumin.
Greenish-blue gastric content: literature review and case report on acute copper sulfate poisoning
Workup including viral hepatitis, CA-19, ceruloplasmin, anti-mitochondrial antibody, tissue transglutaminase IgA, alpha-fetoprotein, and alpha-1antitrypsin was unremarkable.
Refractory Lactic Acidosis in Small Cell Carcinoma of the Lung
Extensive workup for other causes of liver injury was negative including viral hepatitis serologies, anti-nuclear antibodies, smooth muscle antibodies, anti-mitochondrial antibodies, ceruloplasmin, acetaminophen level, and iron studies.
A Rare Case of Rivaroxaban Causing Delayed Symptomatic Hepatocellular Injury and Hyperbilirubinemia
The serum ceruloplasmin was normal, ruling out Wilson's disease; hereditary hemochromatosis DNA mutation was absent; ANA titers were negative; and antismooth muscle antibodies were weakly positive.
Synthetic Cannabinoid Abuse and a Rare Alpha-1-Antitrypsin Mutant Causing Acute Fulminant Hepatitis: A Case Report and Review of the Literature
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