spondylitis
[spon″dĭ-li´tis] inflammation of the
vertebrae, usually a serious and chronic disorder. It may be associated with tuberculosis of the bones, in which case it is called
pott's disease. The vertebrae become eroded and collapse, causing
kyphosis. Spondylitis may also be associated with other infectious diseases, such as
brucellosis, in which the intervertebral disks and the vertebrae are affected and sometimes destroyed; this is one cause of
ankylosing spondylitis, a particularly serious variety.
ankylosing spondylitis (
Bekhterev's spondylitis) a form of
rheumatoid arthritis that affects the spine, characterized by inflammation of the facet joints and inflammatory changes of the stabilizing ligaments of the spine (
enthesopathy). It affects males almost exclusively. There is stiffening of spinal joints and ligaments, so that movement becomes increasingly painful and difficult. When it runs its full course, it results in bony ankylosis of the vertebral joints, which may extend to the ribs and limit the flexibility of the rib cage, so that breathing is impaired. Called also
Marie-Strümpell disease or
spondylitis and
rheumatoid spondylitis.

Typical posture of patient with ankylosing spondylitis. From Copstead and Banasik, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
an·ky·los·ing spon·dy·li·tis
[MIM*106300] arthritis of the spine, resembling rheumatoid arthritis, which may progress to bony ankylosis with ossification of the anterior and posterior longitudinal ligaments; the disease is more common in males, often with the rheumatoid factor absent and the HLA antigen present. There is a striking association with the B27 tissue type and the strong familial aggregation suggests an important genetic factor, perhaps inherited as an autosomal dominant [MIM*106300]; the mechanism, however, remains obscure.
Farlex Partner Medical Dictionary © Farlex 2012
Marie,
Pierre, French neurologist, 1853-1940. Brissaud-Marie syndrome - see under
Brissaud Charcot-Marie-Tooth disease - see under
Charcot Debré-Marie syndrome - see under
Debré Foix-Cavany-Marie syndrome - see under
Foix Marie ataxia - obsolete term for a variety of non-Friedreich hereditary ataxias.
Marie-Leri syndrome - swelling of deformed joints.
Marie-Sainton syndrome - excessive head development. Synonym(s): cleidocranial dysplasia; cleidocranial dysostosis
Marie II syndrome - endocrine and neurologic disorders.
Strümpell-Marie disease - see under
Strümpell
Strümpell,
Ernst Adolf von, German physician, 1853-1925. Strümpell disease - arthritis and osteitis deformans involving the spinal column. Synonym(s): acute epidemic leukoencephalitis; spondylitis deformans
Strümpell-Marie disease - arthritis of the spine, resembling rheumatoid arthritis, that may progress to bony ankylosis. Synonym(s):
ankylosing spondylitis;
Marie-Strümpell disease Strümpell phenomenon - dorsal flexion of the great toe in a paralyzed limb when the limb is drawn up against the body, flexing knee and hip. Synonym(s): tibial phenomenon
Strümpell reflex - stroking the abdomen or thigh causes flexion of the leg and adduction of the foot.
Medical Eponyms © Farlex 2012