necrobiosis

[nek″ro-bi-o´sis]

the physiologic death of cells; a normal mechanism in the constant turnover of many cell populations. Called also bionecrosis. adj., adj necrobiot´ic.

necrobiosis lipoi´dica a dermatosis characterized by patchy degeneration of the elastic and connective tissue of the skin with degenerated collagen occurring in irregular patches, especially in the dermis, most often on the mid or lower shins; usually associated with diabetes.

nec·ro·bi·o·sis

(nek'rō-bī-ō'sis),

1. Physiologic or normal death of cells or tissues as a result of changes associated with development, aging, or use.

2. Necrosis of a small area of tissue.

Synonym(s): bionecrosis

[necro- + G. biōs, life]

Farlex Partner Medical Dictionary © Farlex 2012

necrobiosis

(nĕk′rō-bī-ō′sĭs)

The natural death of cells or tissues through aging, as distinguished from necrosis or pathological death.

nec′ro·bi·ot′ic (-ŏt′ĭk) adj.

necrobiosis

Physiologic cell death seen during normal turnover in bone marrow, endometrium, GI tract and skin.

nec·ro·bi·o·sis

(nek'rō-bī-ō'sis)

1. Physiologic or normal death of cells or tissues as a result of changes associated with development, aging, or use.

2. Necrosis of a small area of tissue.
Synonym(s): bionecrosis.

[necro- + G. biōs, life]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

necrobiosis

Natural death of cells and tissues occurring in the midst of healthy tissue. Natural cell death as opposed to death from disease or injury.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

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References in periodicals archive

y/Sex Foreign Stain IHC Material Results (b) (a) 1 64/M Not identified Negative Negative TC 2 64/F Not identified Negative Not performed TC, ILC 3 49/F Not identified Negative Negative None 4 57/F Not identified Negative Negative TC 5 52/F Not identified Negative Not performed TC Abbreviations: B, necrobiosis; C, colloidal iron stain confirmed increased mucin deposition; E, presence of eosinophils; F, perifollicular lymphohistiocytic infiltrate; G, nonnecrotizing granulomas; IHC, immunohistochemistry; ILC, intralesional corticosteroids; L, left; M, multinucleated giant cells; N, perineurovascular lymphohistiocytic infiltrate; P, elastophagocytosis; R, right; TC, topical corticosteroids.

Wolf isotopic response manifesting as postherpetic granuloma annulare: a case series

Squamous cell carcinoma arising in an area of long-standing necrobiosis lipoidica.

Unsightly rash on shin: what started as a few small red spots was now an 8 x 6 cm well-demarcated red-brown plaque on the patient's shin. Was it linked to her diabetes?

M2 EQUITYBITES-June 25, 2018-Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

Global Banking News-June 25, 2018-Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

M2 PHARMA-June 25, 2018-Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

Processa wins US FDA orphan designation status for PCS499 for Necrobiosis Lipoidica (NL)

Histology is characteristic with histiocytes arranged in palisade around central necrobiosis.

A clinical and demographic study of single lesions in leprosy

These cases were numbers 06 (necrobiosis lipoidica) and 08 (botryomycosis) for the ND dermatitides and numbers 05 (epidermolysis bullosa dermolytic) and 08 (systemic lupus erythematosus) for the SV dermatitides, as listed in Table 1.

Perceptual analysis of the reading of dermatopathology virtual slides by pathology residents

Localized granuloma annulare must be differentiated from the most common annular lesion, tinea corporis, as well as other annular lesions, including necrobiosis lipoidica and erythema migrans.

Confluent annular lesion on the dorsum of the hand

Patients presenting necrobiosis lipoidia, in which thermal sensation may be altered, (43) was not evaluated in the present study nor were comparisons WPT, CPT and WCPI with other diagnostic methods.

Impaired warm and cold perception thresholds in leprosy skin lesions

b) Only 0.3% of patients with necrobiosis develop diabetes mellitus.

AJMH based CPE questionnaire