Necrobiotic granulomas is an another granuloma of unknown etiology in young diabetic people with central fibrinoid necrosis.11
Granuloma annulare is a idiopathic
necrobiotic disorder which has many predisposing factors.
After a 25-year course of
necrobiotic xanthogranuloma with paraproteinemia, this patient died of bacteremia following pancytopenia as he developed myeloma, Dr.
DISCUSSION: The most characteristic histological lesion in granuloma annulare is the
necrobiotic granuloma.
These
necrobiotic nodules are often located subpleurally and surrounded by palisading histiocytes and giant cells.
The acute viral
necrobiotic virus (AVNV) infection in C.farreri induces a dramatic increase in PAH at 6 h postinfection, and PO is the earliest responding endoenzyme to AVNV among the 7 determined enzymes (Xing et al.
Differential diagnosis will be tendinous xanthoma,
necrobiotic granuloma, foreign body granuloma, epidermoid cyst, knuckle pad, fibroma of tendon sheath, lipoma and ganglion cyst [8].
Noninfectious cystitis includes interstitial cystitis, eosinophilic cystitis, drug-induced cystitis, and postsurgical
necrobiotic granulomas.
Necrobiotic granulomas of the uterine cervix: a probable postoperative reaction.
Granulomatous bronchiolitis with
necrobiotic pulmonary nodules in Crohn's disease.
In particular, isolated rheumatoid nodules or
necrobiotic granulomas (deep granuloma annulare) have a decided potential for this mimicry, vis-a-vis the alternative diagnosis of epithelioid sarcoma.