Lang·hans cells

(lahng'hahnz),

1. multinucleated giant cells seen in tuberculosis and other granulomatous diseases; the nuclei are arranged in an arciform manner at the periphery of the cells; Synonym(s): Langhans-type giant cells

2. Synonym(s): cytotrophoblastic cells

Farlex Partner Medical Dictionary © Farlex 2012

Lang·hans cells

(lahng'hahnz selz)

1. Multinucleated giant cells seen in tuberculosis and other granulomatous diseases; the nuclei are arranged in an arciform manner at the periphery of the cells.
Synonym(s): Langhans-type giant cells.

2. Synonym(s): cytotrophoblastic cells.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Langhans,

Theodor, German pathologist, 1839-1915.

Langhans cells - multinucleated giant cells seen in tuberculosis and other granulomas. Synonym(s): cytotrophoblastic cells; Langhans-type giant cells

Langhans layer - the inner layer of the trophoblast. Synonym(s): cytotrophoblast

Langhans stria - fibrinoid that accumulates on the chorionic plate between the bases of placental villi during the first half of pregnancy.

Langhans-type giant cells - Synonym(s): Langhans cells

Medical Eponyms © Farlex 2012

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References in periodicals archive

Lord, "Langhans cells of human arterial intima: Uniform by stellate appearance but different by nature," Tissue & Cell, vol.

Vascular Calcification in Chronic Kidney Disease: The Role of Inflammation

Caption: Figure 2: Histopathological picture showing epithelioid cells, Langhans cells, and foci of caseous necrosis.

Tubercular Ulcer of Tongue in an Elderly Patient Masquerading as a Traumatic Ulcer

HPE showed Langhans cells and AFB staining positive for two.

HPE of the tissue showed positive for Langhans cells with AFB +ve.

Hospital outbreak of post caesarean wound infection with atypical mycobacteria

In mid-borderline leprosy, grenz zone in 75%, AFB in 50% cases by ZN stain and 75% cases by modified Fite stain, macrophage predominance of infiltrate in 75% cases, perivascular and periappendiceal infiltrate in 50%, immature epithelioid granuloma and obliteration of nerve by granuloma in 33.33% of cases, and lymphocyte predominance of infiltrate, macrophage granuloma, and presence of Langhans cells each in 25% of cases were seen.

An institution-based observational study to identify sensitive histopathological parameters in leprosy

Macrophages in granulomas may fuse to form multinucleated giant cells, Langhans cells. Local secretion of the cytokine TNF is required for optimal granuloma structure.

Immunological protection against tuberculosis

The numerous epithelioid granulomas contained Langhans cells and foreign body giant cells, while the necrotizing lesions contained neutrophilic and eosinophilic infiltrates.

Blastomycosis in Ontario, 1994-2003