border

[bor´der]

a bounding line, edge, or surface.

brush border a specialization of the free surface of a cell, consisting of minute cylindrical processes (microvilli) that greatly increase the surface area.

Brush border, characterized by closely packed microvilli. From Dorland's, 2000.

vermilion border the exposed red portion of the upper and lower lips.

brush bor·der

the apical epithelial surface bearing closely packed microvilli about 2 mcm long, such as occur on the cells of the proximal tubule of the nephron.

Synonym(s): limbus penicillatus

Farlex Partner Medical Dictionary © Farlex 2012

A specialized portion of the free or apical aspect of certain epithelial cells—e.g., of the GI tract—consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx—which is rich in hydrolytic enzymes

brush border

Physiology A specialized portion of the free or apical aspect of certain epithelial cells–eg, of the GI tract, consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx–which is rich in hydrolytic enzymes

brush bor·der

(brŭsh bōr'dĕr)

An epithelial surface bearing closely packed microvilli about 2 mcm long, such as occurs in the proximal tubule of the nephron.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

brush border

see MICROVILLUS.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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References in periodicals archive

Bacteria were not observed in the ectoperitrophic space or attached to the brush border of the MGT in sections examined by LM and TEM.

Peritrophic membrane of the penaeid shrimp Sicyonia ingentis: structure, formation, and permeability

The active cap region of the ABO is composed of tall, mitochondria-rich cells with distinct brush borders at their apicies, surrounding a hemolymph-containing central sinus.

Vacuolar-type ATPase in the Accessory Boring Organ of Nucella lamellosa (Gmelin) (Mollusca: Gastropoda): Role in Shell Penetration

Furthermore, when 2 to 3 yr-old sheep were intraduodenally infused with a 30 mM glucose solution for 4 d, glucose transporter activity in brush border membrane vesicles increased 40 to 80-fold.

Understanding starch utilization in the small intestine of cattle

It has been suggested that the brush border cytoskeleton is responsible for the shape, stability and motility of microvilli, composed mainly of actin, myosin and filament binding proteins (Mooseker, 1985).

Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics

These discrepancies may be attributable to proteolytic degradation of trehalase in urine, although the stability of trehalase in the renal brush border membrane or urine is not clear.

ELISA for urinary Trehalase with monoclonal antibodies: a technique for assessment of renal tubular damage

Different pig phenotypes affect adherence of Escherichia coli to jejunal brush borders by K88ab, K88ac and K88ad antigen.

Identification and screening of gene(s) related to susceptibility to enterotoxigenic Escherichia coli F4ab/ac in piglets

PCT was looked up for loss of brush border and cellular debris in lumen.

CINNAMON EXTRACT PROVIDES MORE NEPHROPROTECTION THAN GREEN TEA IN BISPHENOL - A INDUCED DAMAGE IN PROXIMAL AND DISTAL KIDNEY TUBULES

Diabetic Nephropathy Associated with a Decrease in Brush Border Villin Levels in Meprin Expressing Kidneys.

Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes

The brush border enzymes in the microvilli complete the last phase of digestion before the sugars are absorbed into the body.

Enzymes Play an Important Role in Digestion: Digestive enzymes break down foods into the nutrients that fuel your body

This is in agreement with the study conducted by Mohamed et al., who reported increase in the diameter of PCTs of male albino rats exposed to lead acetate both pre- as well as post-natally.14 One of the reasons for increase in the diameter of PCTs may be the loss of brush border due to oxidative stress produced by lead.

Lead-induced morphometric changes in the kidneys of albino rats ameliorated by ginkgo biloba extract (EGb 761)

Lactose which is digested by the brush border enzyme lactase is one of the poorly absorbed short-chain carbohydrates, often referred as FODMAPs (fermentable, oligo-, di-, monosaccharides and polyols).

Diagnostic and Research Aspects of Small Intestinal Disaccharidases in Coeliac Disease