Upon ingestion,
amygdalin is hydrolyzed to cyanide by beta-glucuronidase in the small intestine [2].
Prunus serotina
amygdalin hydrolase and prunasin hydrolase.
Characteristics Results [beta]-Galactosidase - Arginine hydrolase + Lysine decarboxylase - Ornithine decarboxylase - The use of citric acid - [H.sub.2]S production - Urease - Tryptophan deaminase + Indole production - Acetoin production + Characteristics Results Gelatinase - Glucose fermentation/oxidation - Mannitol Fermentation/oxidation + Inositol fermentation/oxidation - Sorbitol fermentation/oxidation - Rhamnose fermentation/oxidation - sucrose fermentation/oxidation - Melibiose fermentation/oxidation -
Amygdalin fermentation/oxidation + Arabinose fermentation/oxidation - +: presence of a trait; -: absence of a trait.
Test Reaction Fermentation/oxidation Glucose + Mannitol + Sucrose +
Amygdalin + Inositol - Sorbitol - Rhammose - Melibiose - Arabinose - Acetoin production (Voges Proskauer) - Lysine decarboxylase + Ornithine decarboxylase + Citrate utilization + Tryptophane deaminase + Indole production + Gelatinase + Oxidase + P-galactosidase - H2S production - Urease - Nitrate/Nitrite reduction - Martins, ML.
API 20E[R] strips-API 20E[R] strips include enzymatic tests for fermentation or oxidation of glucose, mannitol, inositol, sorbitol, rhamnose, saccharose, melibiose,
amygdalin, and arabinose, along with nitrate reduction to nitrite and nitrate reduction to nitrogen gas.
Laetrile, a compound chemically related to
amygdalin, and found naturally in the pits of apricots and various other fruits, gained notoriety as a focus of political activities intended to abolish the laws protecting Americans from quackery.
The B17 pills - called Laetrile or
Amygdalin - are illegal to sell in the US after trials proved they had no effect on the killer disease.
Plums also contain insignificantly low levels of a substance called
amygdalin, a compound that produces cyanide.
Davignon, "A Clinical Trial of
Amygdalin (Laetrile) in the Treatment of Human Cancer," New England Journal of Medicine 306, no.
Banned in the US, laetrile is rebounding on the Internet, sometimes sold under the aliases
amygdalin or Vitamin B17.
However, some seeds or pits (apricots, apples, cherries, plums, pears, and bitter almond) contain a small amount of
amygdalin, which releases cyanide, a poison.
Similarly, Colorado and New Jersey both permit the prescription use of the unapproved Laetrile (
amygdalin) provided warnings are given to patients.