plexiform neurofibroma

plex·i·form neu·ro·fi·bro·ma

a type of neurofibroma, representing an anomaly rather than a true neoplasm, in which the proliferation of Schwann cells occurs from the inner aspect of the nerve sheath, thereby resulting in an irregularly thickened, distorted, tortuous structure; in some instances, the process extends along the course of the nerve and may eventually involve the spinal roots and the spinal cord; seen most frequently in neurofibromatosis.

Synonym(s): fibrillary neuroma, plexiform neuroma

Farlex Partner Medical Dictionary © Farlex 2012

plexiform neurofibroma

A benign, non-encapsulated tumour composed of proliferating axons, Schwann cells, fibroblasts and perineurial cells.
 
Types
• Plexiform neurofibromas may cause a marked deformation and enlargement of a body part or region, an event known as elephantiasis neuromatosa.
• Cutaneous and subcutaneous neurofibromas are seen in type-1 neurofibromatosis (NF), are non-circumscribed, thick, irregular, may cause disfigurement by entwining critical structures, and are usually associated with type-1 NF.
 
Locations
Orbit, neck, back, inguinal region.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

plex·i·form neu·ro·fi·bro·ma

(plek'si-fōrm nūr'ō-fī-brō'mă)

A type of lesion, representing an anomaly rather than a true neoplasm, in which the proliferation of Schwann cells occurs from the inner aspect of the nerve sheath; seen most frequently in neurofibromatosis.
Synonym(s): plexiform neuroma.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012