We believe we now have the basis to pursue COPD wasting as an initial indication for ThGRF and our analysis indicates that this is potentially a very large market.
The overall patient population was representative of a non-obese COPD population and included patients with various degrees (mild to severe) of COPD severity, the pulmonary component of the disease, as defined by the American Thoracic Society criteria, and various degrees of muscle depletion, or wasting, the peripheral component of the disease, as defined by Body Mass Index (BMI) or Fat-Free Mass Index (FFMI).
In this regard, ThGRF is currently developed as the first compound for the treatment of muscle depletion, or wasting, associated with COPD.
The epicenter of Chronic Wasting Disease is the Foothills Wildlife Research Facility in Fort Collins, Colorado, operated by the state's Department of Wildlife.
He believes Chronic Wasting Disease "must be an extremely virulent strain" to jump the species barrier.
"That's the theory," says Michael Miller, a veterinarian and Chronic Wasting Disease expert at the Foothills facility.