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transcytosis

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trans·cy·to·sis

(tranz'sī-tō'sis),
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis). The transport mechanism by which most proteins reach the Golgi apparatus or the plasma membrane; the vesicles targeted toward lysosomes and secretory storage granules appear to be coated with clathrin.
Synonym(s): cytopempsis, vesicular transport
Farlex Partner Medical Dictionary © Farlex 2012

transcytosis

A type of caveolae-mediated vesicular trafficking, in which caveolae transport proteins from the luminal side of an endothelial cell to the interstitial compartment for subsequent uptake by surrounding tissue.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

trans·cy·to·sis

(tranz-sī-tō'sis)
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis).
Synonym(s): vesicular transport.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive
CNS delivery via adsorptive transcytosis. AAPS J 2008;10:455-72.
Imaging Gliomas with Nanoparticle-Labeled Stem Cells
A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier.
Total Cholesterol Levels and Sustained Attention in University Undergraduates
Tuma, "Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function," Molecular and Cellular Biochemistry, vol.
Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis. Am J Pathol.
Zika Virus: The Agent and Its Biology, With Relevance To Pathology
The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo.
Dasatinib-induced chylothorax in chronic myeloid leukemia
Tan, "Toll-like receptor 2-mediated peptidoglycan uptake by immature intestinal epithelial cells from apical side and exosome-associated transcellular transcytosis," Journal of Cell Physiology, vol.
Short-Term Regulation of Fc[gamma]R-Mediated Phagocytosis by TLRs in Macrophages: Participation of 5-Lipoxygenase Products
Insulin production by cells in the brain is somewhat controversial, although insulin is delivered from the blood to the brain by receptor-mediated transcytosis. The insulin receptor rarely induces glucose uptake by brain cells.
The LDL Receptor-Related Protein 1: At the Crossroads of Lipoprotein Metabolism and Insulin Signaling
However, the parallel existence of transcytosis cannot be ruled out.
From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells
Li et al., "Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis," American Journal of Physiology--Endocrinology and Metabolism, vol.
Knockout of Vasohibin-1 Gene in Mice Results in Healthy Longevity with Reduced Expression of Insulin Receptor, Insulin Receptor Substrate 1, and Insulin Receptor Substrate 2 in Their White Adipose Tissue
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