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pyknosis

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pyknosis

 [pik-no´sis]
a thickening, especially the degeneration of a cell in which the nucleus shrinks in size and the chromatin condenses to a solid, structureless mass or masses. adj., adj pyknot´ic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pyk·no·sis

(pik-nō'sis),
A thickening or condensation; specifically, a condensation and reduction in size of the cell or its nucleus, usually associated with hyperchromatosis; nuclear pyknosis is a stage of necrosis.
[pykno- + G. -osis, condition]
Farlex Partner Medical Dictionary © Farlex 2012

pyk·no·sis

(pik-nō'sis)
A thickening or condensation; specifically, a condensation and reduction in the size of the cell or its nucleus, usually associated with hyperchromatosis; nuclear pyknosis is a stage of necrosis.
[pykno- + G. -osis, condition]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

pyk·no·sis

(pik-nō'sis)
A thickening or condensation; specifically, a condensation and reduction in the size of the cell or its nucleus, usually associated with hyperchromatosis.
[pykno- + G. -osis, condition]
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive
Histopathological findings in liver mostly showed vascular degeneration associated with nuclear pyknosis; also it is found in liver marked depletion and congestion of the portal vein accompanied with nuclear pyknosis.
It is known that ooplasmic vacuolation and GC pyknosis are observed simultaneously with early antrum formation in atretic follicles (21, 33).
Panels A-G show that the morphology of Saos-2 cells cultured in different extracts for 72 h was normal and healthy, similar to that of the negative control, but the 5% DMSO positive control revealed many apoptotic cells, manifested as nuclear pyknosis (panel H).
All the follicles were classified as either healthy or atretic, respectively, according to the absence or presence of signs of oocyte and/or granular degeneration such as pyknosis of the nucleus, infolding of the cell wall in oocyte, ingression of granulosa cells within the antral cavity, pulling away of granulosa cells from the basement membrane, infolding or thickening of base membrane and uneven layers of granulosa cells (27).
In line with our in vitro results, the subcutaneous xenogeneic or allogeneic co-administration of different intestinal adenocarcinoma cell line in murine model with sesquiterpene compound, Ferutinin, resulted in slower tumor growth rate with concurrent nuclear pyknosis and apoptosis (Arghiani et al.
In this condition, the superficial portion of the squamous epithelium becomes necrotic, giving a two-tone appearance to the mucosa, with pyknosis resembling parakeratosis and necrosis of the superficial layers (Figure 3, A and B).
(10, 11) These include: islands of well differentiated squamous cells present at all levels of the epithelium; disorganized cellular polarity; cellular pleomorphism; presence of nucleoli in some cells; frequent pyknosis; and individual cell keratinisation.
Malathion administration also reduced epididymal weight [63], whereas increased weight of epididymis and cellular necrosis, nuclear pyknosis, and a deleterious effect on the structural integrity following methyl parathion exposure were observed [61, 64].
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