primary lateral sclerosis

pri·mar·y lat·er·al scle·ro·sis

considered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion.

Synonym(s): lateral spinal sclerosis

Farlex Partner Medical Dictionary © Farlex 2012

pri·mar·y lat·er·al scle·ro·sis

(prī'mar-ē lat'ĕr-ăl skler-ō'sis)

Considered by many to be a subset of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski sign are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012