Medical

prealbumin

pre·al·bu·min

(prē'al-byū'min),
1. A protein component of plasma having a molecular weight of about 55,000 and containing 1.3% carbohydrate; estimated plasma concentration is 0.3 g per 100 mL; abnormal levels of prealbumin are found in cases of familial amyloidosis. Synonym(s): transthyretin
2. The protein-containing zone observed in zone electrophoresis of serum that migrates more rapidly than serum albumin.
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References in periodicals archive
(6) A pattern of laboratory results with normal AST and ALT, yet abnormal markers of protein synthesis (prolonged coagulation time, low albumin, or prealbumin levels), is consistent with this clinical situation.
K/DOQI guidelines recommend using blood panels for nutritional testing, which may include serum albumin, serum prealbumin, BUN, serum creatinine, and total cholesterol.
Prealbumin, also known as transthyretin, is a more appropriate nutritional marker in the acutely ill adult because it has a 2-day half-life.
Results of serum indices of nutritional and inflammatory status showed significantly higher levels of CRP, [Alpha]-1AG, haptoglobin and IgA, and lower levels of albumin, Ca and prealbumin in group Inf than in group N-Inf, thus confirming the inflammatory status of group Inf EP.
Falcons with confirmed aspergillosis showed significantly lower prealbumin values, which is a novel finding.
In cirrhotic serum we observed decreased expression of intera-trypsin inhibitor heavy chain H4 (ITIH4) fragments, [alpha]1 antichymotrypsin, apolipoprotein L1 (Apo L1), prealbumin, albumin, paraoxonase/arylesterase 1, and zinc-[alpha]2-glycoprotein and increased expression of CD5 antigenlike protein (CD5L) and [beta]2 glycoprotein I ([beta]2GPI).
Another facility is equipped to perform an excellent nutrition assessment assay (prealbumin) on its new automated chemistry system, but this hospital, too, does not have adequate professional nutrition staff to make use of the test results.
Dietitians will monitor nutritional labs such as albumin, prealbumin, and transferrin on a regular basis to evaluate the effectiveness of the nutritional plan.
The usefulness of albumin and prealbumin as nutritional markers has already been validated [23].
Marked differences in fraction migration were found between the Beckman/Helena and Sebia systems, which manifested as a large decrease in prealbumin and an increase in [[alpha].sub.1] globulins in the latter system.
Vaks entitled "Evaluation of Assigned Value Uncertainty for Complex Calibrator Value Assignment Processes: A Prealbumin Example" (Clin Chem 2007;53:735-41), contains several errors.
Serum proteins such as albumin, prealbumin, and transferrin are reduced in states of protein-calorie malnutrition (Evans-Stoner, 1997).
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