polioencephalomalacia

(pō'lē-ō-en-sef'ă-lō-mă-lā'shē-ă),

Cerebrocortical necrosis in sheep and goats, also seen in cattle, deer, and antelope. Associated with thiamine deficiency, water deprivation-sodium ion toxicosis, lead poisoning, and particularly with high dietary sulfur levels leading to high hydrogen sulfide and acetic acid levels in the rumen, which adversely affect carbohydrate metabolism.

Synonym(s): cerebrocortical necrosis

Farlex Partner Medical Dictionary © Farlex 2012

References in periodicals archive

Association of excess sulfur intake and an increase in hydrogen sulfide concentrations in the ruminal gas cap of recently weaned beef calves with polioencephalomalacia. J Am Vet Med Assoc.

Ruminal hydrogen sulfide concentration determined by a simple sulfide detector tube method in bovine kept under extensive system/Concentracao ruminal de sulfeto de hidrogenio mensurada por tubos colorimetricos em bovinos nelore sadios criados extensivamente/Evaluacion de la concentracion ruminal de sulfuro de hidrogeno por tubos colorimetricos en bovinos nelore saludables creados de forma extensiva

The intramenineal hemorrhages (not related to euthanasia) was associated with focally extensive polioencephalomalacia. Onhistopathology, a single area of the meninges showed a massive blood clot, while the subjacent gray matter was markedly rarefied.

Like most cases of polioencephalomalacia, the pathology observed in case D was most likely due to a thiamine deficiency.

Polioencephalomalacia and enterotoxemia are sub-acute results of grain overload.

Grain overload and secondary effects as potential mortality factors of moose in North Dakota

Polioencephalomalacia (PEM) is a disorder of sheep and cattle that appears to be caused by the ingestion of substances that create a thiamin deficiency.

Chapter 16 Feeding beef

Ruminal acidosis combined with excess sulfur intake may lead to a disorder called polioencephalomalacia, which is discussed in Chapter 9.

Polioencephalomalacia (PEM) is a disorder occurring most commonly in sheep and cattle that is caused by a thiamin deficiency.

Chapter 20 Feeding sheep

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