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paraneoplastic syndrome

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paraneoplastic syndrome

 [par″ah-ne″o-plas´tik]
a collective term for disorders arising from metabolic effects of cancer on tissues remote from the tumor; such disorders may, for example, appear as primary endocrine, hematologic, or neuromuscular disorders.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

par·a·ne·o·plas·tic syn·drome

a syndrome directly resulting from a malignant neoplasm, but not resulting from the presence of tumor cells in the affected parts.
Farlex Partner Medical Dictionary © Farlex 2012

paraneoplastic syndrome

Oncology A co-morbid condition due to the indirect–remote or 'biologic' effects of malignancy, which may be the first sign of a neoplasm or its recurrence; PSs occur in > 15% of CAs, are caused by hormones, growth factors, biological response modifiers, and other as-yet unidentified factors, and may regress with treatment of the primary tumor. See Ectopic hormone.
Paraneoplastic syndromes
GI tract, eg anorexia, vomiting, protein-losing enteropathy, liver disease
Hematologic, eg leukemoid reaction, reactive eosinophilia, peripheral 'cytoses or 'cytopenias, hemolysis, DIC, thromboembolism, thrombophlebitis migrans
Hormonal effects
Metabolic disease, eg lactic acidosis, hypertrophic pulmonary osteoarthropathy, hyperamylasemia, hyperlipidemia
Neuromuscular, eg peripheral neuropathy, myopathy, CNS, spinal cord degeneration, inflammation
Renal, eg nephrotic syndrome, uric acid nephropathy
Skin, eg bullous mucocutaneous lesions, acquired ichthyosis, acanthosis nigricans, dermatomyositis
Others, eg callus formation, hypertension, and amyloidosis
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

par·a·ne·o·plas·tic syn·drome

(par'ă-nē-ō-plas'tik sin'drōm)
A syndrome directly resulting from a malignant neoplasm, but not resulting from the presence of tumor cells in the affected parts.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Paraneoplastic syndrome

A set of symptoms that is associated with cancer but is not directly caused by the cancer.
Mentioned in: Thymoma
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

par·a·ne·o·plas·tic syn·drome

(par'ă-nē-ō-plas'tik sin'drōm)
Syndrome directly resulting from a malignant neoplasm, but not resulting from presence of tumor cells.
Medical Dictionary for the Dental Professions © Farlex 2012
Mentioned in
References in periodicals archive
Timely and accurate diagnosis and treatment of paraneoplastic syndromes can greatly affect patient's clinical outcomes.
Metastatic Prostate Cancer Manifesting as Cholestatic Jaundice: A Case Report and Review of the Literature
Wang, "Refractory diarrhea: A paraneoplastic syndrome of neuroblastoma," World Journal of Gastroenterology, vol.
Immune Thrombocytopenia in a Child with Neuroblastoma
A case of paraneoplastic syndrome mimicking adult-onset Still's disease.
Adult onset still's disease as a paraneoplastic syndrome: a case report and review of the literature
Nevertheless, the association of a neuroendocrine tumor with a paraneoplastic syndrome may contribute to marked disease morbidity.
Small cell neuroendocrine carcinoma of rectum with associated paraneoplastic syndrome: a case report
Paraneoplastic syndromes may be associated with mood changes and other psychiatric symptoms.
A case of sudden psychosis
A surgical operation may determine the route of depressive disorders, when they are caused by endocrine tumours or paraneoplastic syndromes.
"Endo-depression" in surgical patients: why surgeons may more effectively treat depression
The most frequent causes of spinal myoclonus are spinal cord compression, tumour, vascular myelopathy, infection, demyelinating disease, paraneoplastic syndrome and trauma.
Spinal myoclonus following intrathecal anaesthesia with prilocaine
Final diagnosis of 'Nephrotic Syndrome as a Paraneoplastic syndrome in a patient with Thymic mass' was made and planned for Thymectomy with excisional biopsy.
Nephrotic syndrome as paraneoplastic syndrome in a patient with thymic mass
POEMS syndrome is a rare paraneoplastic syndrome driven by neoplastic plasma cells.
Polyneuropathy as Novel Initial Manifestation in a Case of "Nonsecretory" POEMS Syndrome with Sjogren's Syndrome
Stiff person syndrome (SPS) is a rare neuroimmunological disorder identified as an autoimmune or paraneoplastic syndrome [1].
Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome
In rare instances, aberrant hormone production by the tumor cells may result in a paraneoplastic syndrome. Outcome and management are different for each tumor type, but surgery is generally used for all, with chemotherapy added for the atypical carcinoid and small or large cell neuroendocrine carcinomas.
Neuroendocrine tumors of the larynx
Thereby, the patient was finally diagnosed to have SVC syndrome due to thrombosis as a paraneoplastic syndrome in bronchogenic carcinoma.
Superior vena cava syndrome due to thrombosis: a rare paraneoplastic presentation of bronchogenic carcinoma
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