somatostatinoma syndrome

somatostatinoma syndrome

Oncology A paraneoplastic syndrome caused by ectopic somatostatin secretion Clinical Vomiting, hypochlorhydria, abdominal pain, diarrhea, malabsorption, weight loss, cholelithiasis, ↓ glucose control, causing 2º DM Lab ↑ somatostatin–an inhibitory hormone, evoking reactive ↓ insulin, ↓ glucagon, ↓ gastrin, steatorrhea, anemia

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