microfold cells
microfold cells
specialized intestinal epithelial cells found in association with the lymphoid follicles, as in Peyer patches of the ileum; characterized by elaborate invaginations of their apical cell surface that harbor numerous lymphocytes and macrophages; believed to phagocytose antigens and present them to underlying lymphoid cells.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive
GP2 is found in
microfold cells (M cells) of the follicular-associated epithelium in intestinal Peyer's patches (22).
Generally, some bioactive polysaccharides were considered to modulate systemic immunity through
microfold cells in the follicle-associated epithelium of the Peyer's patch (Volman et al.
(2012) The Ets transcription factor Spi-B is essential for the differentiation of intestinal
microfold cells. Nat.
The physical/chemical barriers composed by IEL, Paneth cells (PC),
microfold cells (M cells) or their products are impaired during the disease and fail to restrain bacterial invasion.
In addition to the pancreatic location of GP2, this glycoprotein was also detected on the
microfold cells (M cells) of intestinal Peyer's patches (PP) representing the follicle-associated epithelium (FAE) in the intestine [23].
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