Propofol and
methohexital as anesthetic agents for electroconvulsive therapy (ECT): a comparison of seizure-quality measures and vital signs.
If catheters were found disconnected or otherwise suspected to have been compromised (as indicated by, e.g., lack of responding during cocaine maintenance sessions, observed swelling, unusual difficulty or ease of injection during presession flush), patency was tested using an acute dose of
methohexital (0.5 mg/kg; Brevital, Portage Pharmacy, Portage, Michigan) delivered via bolus injection through the catheter, and the animal was subsequently observed for prototypic signs of acute administration of a rapid-onset, short-acting barbiturate (i.e., loss of righting reflex and lack of muscle tone).
Propofol as compared to
methohexital has shown improved cognitive performance after anesthesia but statistical significance has been observed in only two cognitive trials.
(24) By 2013, propofol had replaced the short-acting barbiturates, thiopental, and
methohexital, as the preferred induction agent for general anesthesia in over 80% of U.S.
IV pentobarbital, rectal
methohexital and thiopental are the barbiturates that have been studied for procedural sedation.
The FDA is adding its warning to the labels of 11 general anesthetics and sedatives, including desflurane, halothane, ketamine, lorazepam injection,
methohexital, pentobarbital, and propofol.
Souron, "Left ventricular performance during propofol or
methohexital anesthesia: isotopic and invasive cardiac monitoring," Anesthesia and Analgesia, vol.
Zabel, "Highly enriched mixtures of
methohexital stereoisomers by palladium-catalyzed allylation and their anaesthetic activity," European Journal of Organic Chemistry, vol.
(24), 2005, Midazolam and ketamine (55) prospective
Methohexital, propofol or observational study midazolam and a narcotic (45) Gamble etal.
Though IgE-mediated hypersensitivity reactions to thiopental, a thiobarbiturate, have been described, no reports of IgE-mediated hypersensitivity reactions to
methohexital, an oxybarbiturate, have been described [11].
General Anesthesia Drugs Market by Molecule (Propofol, Benzodiazepines, ketamine(s(+) ketamine HCl),
Methohexital Sodium), route of administration (Intravenous, Inhalational), Supply Chain (GPOs, Distributors), Competitive - Analysis Forecast to 2020
Hippocampal memory function as reflected by the intracarotid sodium
methohexital Wada test.