Key words : Alanine aminotransferase, erythrocytopenia,
leukocytopenia, nitrates, sorghum toxicity.
LEUKOCYTOPENIA, THROMBOCYTOPENIA, MEAN CORPUSCULAR VOLUME
[5] Both interferon and ribavirin are potentially toxic with side effects including anemia, cough and shortness of breath, rash, pruriti s, insomnia, anorexia (ribavirin) [6], flu-like symptoms, nausea, diarrhea, alopecia,
leukocytopenia, thyroiditis, thrombocytopenia and psychiatric symptoms (interferon).
This observation further stresses the importance of microscopic clarification of samples with unexplained
leukocytopenia.[16] Most of the FP samples exhibited elevated WBC counts, with myeloid precursor cells on microscopic examination, most probably representing reactive conditions.
In humans, SFTS begins with a high fever, marked thrombocytopenia and
leukocytopenia, and a high serum viral load, followed by multiorgan dysfunction, which may be a consequence of systemic inflammatory responses and disseminated intravascular coagulation (9,10).
Exclusion criteria included additional diseases in the hip (such as primary osteoarthritis, rheumatoid arthritis), skin lesions around the hip, lumbar disc herniation, diabetes, tuberculosis, chronic infection, coagulation dysfunction, anemia, and
leukocytopenia. HIV infection was confirmed by enzyme-linked immunosorbent assays and Western blotting analysis.
Laboratory investigations showed pancytopenia picture with
leukocytopenia (white blood cells 3.1x109/L), anaemia (haemoglobin 7.7 g/dL) and thrombocytopenia (platelets 127x109/L).
(4,5) In addition, some patients present with severe baseline thrombocytopenia and
leukocytopenia due to hypersplenism that preclude initiation of IFN-based therapy.
None of the six patients had thrombocytopenia and only one had
leukocytopenia at baseline, which did not improve with abatacept treatment.
With reference to a case report the recurrence of HCV has been reported to be associated to
leukocytopenia (Gruener et al., 2007).
IR assisted in restoration of
leukocytopenia after whole mice irradiation with significant reduction of serum TNF-[alpha], IL-1[beta], and IL-6.