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hypoxanthine

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hypoxanthine

 [hi″po-zan´thēn]
an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

hy·po·xan·thine (Hyp),

(hī'pō-zan'thin),
6-Oxypurine; purin-6(1H)-one; a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.
Synonym(s): 6-hydroxypurine
Farlex Partner Medical Dictionary © Farlex 2012

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues.
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive
PCA loading analysis showed higher contributions of Cys-GTdS (Figure 4) and hypoxanthine in the aged beef.
These results suggest that guanine is the major component of the crystal platelets but that a significant amount of hypoxanthine is also present in the structures.
Our study observed that SD significantly increased cerebral adenosine and attenuated its catabolic products (i.e., inosine, hypoxanthine, and xanthine), suggesting that the increased cerebral adenosine were associated with the inhibition of adenosine deaminase in SD.
Parts of the peaks were identified as 1, lactic acid; 2, alanine; 3, valine; 4, leucine; 5, proline; 6, glycine; 7, uracil; 8, fumaric acid; 9, serine; 10, threonine; 11, malic acid; 12, pyroglutamic acid; 13, asparagine; 14, hydroxyproline; 15, creatinine; 16, ornithine; 17, glutamic acid; 18, phenylalanine; 19, ribose; 20, glutamine; 21, hypoxanthine; 22, glucose; 23, hexadecanoic acid; 24, linoleic acid; 25, oleic acid; 26, tryptophan; 27, stearic acid; 28, glucose-6-phosphate; 29, maltose; and 30, cholesterol.
Short-term, culture-adapted parasites (3% hematocrit; RPMI-1640 supplemented with 10% human serum, 0.05 mg/mL hypoxanthine, 2 mg/mL sodium bicarbonate, 2 mg/mL glucose, 0.04 mg/mL gentamicin, 0.3 mg/mL L-glutamine in a 37[degrees]C candle-jar atmosphere) were split for blinded RSA0-3h and K13 genotyping.
Xanthine oxidoreductase (XOR) is part of a group of enzymes known as the molybdenum iron-sulfur flavin hydroxylases; it is an evolutionarily conserved housekeeping enzyme, with a principal role in purine catabolism by catalyzing the two last steps in purine catabolism, forming uric acid from hypoxanthine and xanthine.
Glavin et al separated 7 nucleobase standards; U, T, C, hypoxanthine (HX), A, xanthine (X) and G as N,N-tert-butyl-dimethylsilyl-trifluoroacetamide from 15 m x 0.25 mm id, 5% diphenyl, 95% dimethylpolysiloxane column with the Helium flow rate 1.3 ml/min within 30 min [13].
Xanthine oxidase (XO) belongs to the family of xanthine oxidoreductase; catalyzes the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid.
Most of the impact is on textural quality along with the production of hypoxanthine and formaldehyde.
Cord plasma vasopressin, erythropoietin and hypoxanthine as indices of asphyxia at birth.
Xanthine Oxidoreductase (XOR) is a rate-limiting enzyme of the purine degradation pathway, oxidizing hypoxanthine into xanthine and xanthine into uric acid.
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