Medical

hydroxycobalamin

hy·drox·y·co·bal·a·min

(hī-drok'sē-kō-bal'ă-min)
A chemical compound, also called vitamin B12a, which is the immediate precursor to cyanocobalamin (vitamin B12) in the body and that has also been investigated as an antidote in cyanide poisoning, although it is not currently approved for such use in the U.S.
See also: amyl nitrite, sodium nitrite, sodium thiosulfate
Synonym(s): hydroxocobalamin.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive
Super B contains Hydroxycobalamin, a naturally occurring version of vitamin B12 that assists in promoting heart health, improving cognitive function, and stimulating use of fat and carbohydrates in the body for energy.
Moroni, "Acute cyanide intoxication treated with a combination of hydroxycobalamin, sodium nitrite, and sodium thiosulfate," Journal of Toxicology--Clinical Toxicology, vol.
Since these metabolic alterations strongly suggested a cblC disease, the specific treatment with intravenous hydroxycobalamin (5mg/day), betaine (4g/day), and folic acid (5mg/day) was started on the fourteenth day.
(13) This disorder is treated with infusion of hydroxycobalamin.
Current POM injectable versions available with a UK product licence are; Hydroxycobalamin 1mg/ ml in 1 ml ampoules and Cyanocobalamin 1mg/ml in 1 ml ampoules.
Hydrogen peroxide was rapidly produced by combination of 25 [micro]M hydroxycobalamin and 500 [micro]M ascorbic acid added to cell-free culture medium (containing nutrients including an iron salt).
The red color was due to hydroxycobalamin (Cyanokit[R]), prescribed for cyanide poisoning, and not hemoglobin (1).
Vitamin B12 is available as natural cyanocobalamin and its analogue hydroxycobalamin injections.
A) Intramuscular hydroxycobalamin 1,000-mcg load daily for 1 week, then 1,000 meg monthly.
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