The oxygen-binding properties of hemoglobin were evaluated by examining changes in the conformation of hemoglobin
hematoporphyrin in native erythrocytes by means of Raman spectroscopy using an inVia Raman-scattering spectrometer (Renishaw, United Kingdom) with a short focal distance and high transmission monochromator with a focal distance no longer than 250 mm.
A direct correlation between
hematoporphyrin IX and ROS generation in larvae of C.
Oxygen dependence of
hematoporphyrin derivative-induced photoinactivation of Chinese hamster cells.
'The Sensitizing Action of
Hematoporphyrin,' Biochemische Zeitschrift, 30:276-316, 1911.
Hematoporphyrin photodynamic therapy: Is there truly a future in head and neck oncology?
In addition, photodynamic therapy with
hematoporphyrin derivative (HPD) may be useful in treating these melanomas.
This dye, known initially as
hematoporphyrin derivative (Hpd) and in purified form as Photofrin II, has been used to treat about 5,000 patients worldwide for many kinds of solid tumors, including those of the skin, lung, bladder, eye, head, neck and esophagus.
Joffe, "
Hematoporphyrin derivative uptake and photodynamic therapy in pancreatic carcinoma," Journal of Surgical Oncology, vol.
(7) First genetation include photofrin (most extensively used) and
hematoporphyrin derivatives (HPD).
Effects of light exposure on the uptake and destruction of
hematoporphyrin derivative in Ehrlich carcinoma cell suspension.
In addition, chemical treatment could perhaps yield some
hematoporphyrin, with a loss of fluorescence, whereas enzymatic digestion could produce porphyrin-peptide fragments (X porphyrins) with a loss of stoichiometric relationships.