erythroleukemia

[ĕ-rith″ro-loo-ke´me-ah]

a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.

acute erythroleukemia a form of acute myelogenous leukemia representing erythroleukemia in which malignant leukocyte precursors have proliferated and become predominant.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă),

Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.

Farlex Partner Medical Dictionary © Farlex 2012

erythroleukemia

Di Guglielmo syndrome Hematology An acute myelocytic leukemia–FAB classification, M6, which is usually acquired affecting the elderly, but rarely also AD Clinical Anemia, fever, hepatosplenomegaly, hemorrhagic diathesis Lab ↑ Erythroblasts in circulation, BM, ↑ gammaglobulins, false positive positive rheumatoid factor, ANA, Coombs antiglobulin Genetics Aneuploidy–63%; cytogenetic defects, especially chromosomes 5 and 7 Prognosis Poor. See French-American-British classification.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă)

Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.
Synonym(s): erythroleukaemia.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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References in periodicals archive

Jean et al., "Diosgenin dose-dependent apoptosis and differentiation induction in human erythroleukemia cell line and sedimentation field-flow fractionation monitoring," Analytical Biochemistry, vol.

Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology

Sonic Hedgehog activation is implicated in diosgenin-induced megakaryocytic differentiation of human erythroleukemia cells.

Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells

Nevertheless, in mouse erythroleukemia cells, experimental findings have suggested that activation of JNK is crucial for erythropoietin-induced erythroid differentiation [86, 88].

Natural remedies for the treatment of beta-thalassemia and sickle cell anemia--current status and perspectives in fetal hemoglobin reactivation

Slobin, "Regulation of the utilization of mRNA for eucaryotic elongation factor Tu in Friend erythroleukemia cells," Molecular and Cellular Biology, vol.

Mechanisms of miRNA-mediated gene regulation from common downregulation to mRNA-specific upregulation

Effects of trichostatins on differentiation of murine erythroleukemia cells.

Effects of trichostatin A on in vitro development of porcine embryos derived from somatic cell nuclear transfer

Enhanced natural-killer cell and erythropoietic activities in VEGF-A-overexpressing mice delay F-MuLV-induced erythroleukemia. Blood 2007;109:2139-2146.

Gene expression of VEGF-A and VEGF-C in peripheral blood mononuclear cells of Iranian patients with acute myeloid leukemia / Akut Miyeloid Losemili iranli Hastalarin Periferik Kan Mononukleer Hucrelerinde VEGF-A ve VEGF-C Gen Ekspresyonu

Whilst HDACi were originally discovered by their ability to induce erythroid differentiation of erythroleukemia cells [11,12], the subsequent use of HDACi in cancer therapy has concentrated on its functions as a cytotoxic agent.

Sustained low-dose treatment with the histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells

We and others have shown that alantolactone significantly increased the expression of p53 in HepG2 cells [50, 51] with concomitant increase of its downstream target, the cyclin-dependent kinase inhibitor p21 in adriamycin (ADR) resistant human erythroleukemia cell line K562/ADR [57].

Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone

Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells.

Cardioprotective and Antilipidemic Potential of Cyperus rotundus in Chemically Induced Cardiotoxicity