It has been known that both 5'-GMP-Na and vitamin [D.sub.2],
ergocalciferol, are major substances in the mushrooms.
Although
ergocalciferol was used because it is an FDA-approved medication for the treatment of low vitamin D, cholecalciferol ([D.sub.3]) has been reported to be a more potent vitamin [66] and is currently being used in clinical trials.
In one of the reported cases, the patient had persistent vitamin D deficiency despite treatment with a very high dose of vitamin D (
ergocalciferol 100,000 IU/week).
Ca mg/dL P[O.sub.4] AlkP U/L Age of infant mg/dL Reference values (months) 8.3-10.3 4.5-6.7 70-350 Infant's biochemical data Birth 7.6 7.0 -- 2.5 * 10 5.1 595 3 10.2 5.6 715 4 10.0 -- 412 7 10.3 6.0 347 Maternal biochemical data 3 9.5 4.1 95 PTH 25(OH)D 1,25(OH)D Daily treatment with Age of infant pg/mL ng/mL pg/mL
ergocalciferol (IU) (months) 15-75 >20.0 15-75 Infant's biochemical data Birth -- -- -- -- 2.5 * 120 <13 13 2,000 3 <6.3 17.1 209 800 4 27.9 28.4 -- 800 7 13.2 36.5 77 800 Maternal biochemical data 3 -- 8.7 22.1 -- * Initial presentation.
Their identification and subsequent treatment with cholecalciferol (Vitamin D3) or
ergocalciferol (Vitamin D2) in order to obtain adequate seric levels, allows a greater amount of substrate for the proximal convoluted tubule cells, and then inside improve the synthesis of the active form of vitamin D (calcitriol or 1,25(OH)2D) in patients with CKD without dialysis requirements, avoiding the development of all complications from hyperparathyroidism.
As mentioned previously, forms of vitamin D included vitamin D2 (
ergocalciferol), vitamin D3 (cholecalciferol), calcitriol (1,25-hydroxyvitamin D3), paricalcitol, and doxerocalciferol.
rights to several well-known product lines from Sanofi US: Anzemet (dolasetron mesylate) Injection and Tablets, Claforan (cefotaxime) Injection/IM/IV, Demerol (meperidine hydrochloride) Tablets, Drisdol (
ergocalciferol) Capsules and Oral Solution, Hiprex (methenamine hippurate) Tablets, Lasix (furosemide) Tablets, Norpramin (desipramine hydrochloride) Tablets and Trental (pentoxifylline) Tablets.
Vitamin D-2, sometimes on labels as
ergocalciferol, is from yeast, so it is completely vegan.
These include Anzemet (dolasetron mesylate) Injection and Tablets, Claforan (cefotaxime) Injection/IM/IV, Demerol (meperidine hydrochloride) Tablets, Drisdol (
ergocalciferol) Capsules and Oral Solution, Hiprex (methenamine hippurate) Tablets, Lasix(furosemide) Tablets, Norpramin (desipramine hydrochloride) Tablets and Trental (pentoxifylline) Tablets.
These results are different from the findings by Leaf and colleagues, where the authors gave VD repletion therapy (
ergocalciferol 50 000 IU/week) for 8 weeks without calcium supplementation.