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emodin

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em·o·din

(em'ō-din),
A catharitc found in crystalline form in rhubarb, senna, cascara sagrada, and other purgative drugs.
Synonym(s): 1, 3, 8-trihydroxy-6-methylanthroquinone, archin, frangulic acid
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emodin

(ĕm′ə-dĭn′)
n.
An orange crystalline compound, C15H10O5, that is obtained from rhubarb and other plants and has cathartic, anti-inflammatory, and anticancer properties.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
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References in periodicals archive
A variety of miRNAs were found to modulate the efficacy of emodin, such as miR-126 (12), miR-34a (13), and miR-199a (14).
Five chemicals caused statistically significant decreases in ATP content and did not affect growth across the tested concentrations (diphenylurea, emodin, thiadiazuron, niflumic acid, and rifapentine).
Representative chromatograms are shown in Figure 3, including a blank plasma and hippocampus sample (Figures 3(a) and 3(d)), plasma and hippocampus containing curcumin and emodin standard (Figures 3(b) and 3(e)), and a plasma and hippocampus sample obtained 4 h and 2 h, respectively, after intranasal administration of curcumin-loaded thermoreversible gel (Figure 3(c)).
By means of spectroscopic methods and in comparison with the reported data, the structure of the known compounds was identified as torachrysone 8-O-[beta]-D-glucopyranoside (2), pleuropyrone A (4), emodin (5), emodin 8-O-glucopyranoside (6), physcionin (7), resveratrol (8), 2,3,5,4'-tetrahydroxy stilbene-2-O-[beta]-glucoside (9), benzyl gentiobioside (10), and catechin (11).
Buckthorn leaves also contain the secondary metabolite emodin (Seltzner and Eddy, 2003).
Among all constituents in rhubarb, the anthraquinones (including physcion, rhein, emodin, chrysophanol, and aloe-emodin) play a dominant role for the medicinal properties of rhubarb and are regarded as important active ingredients with extensive pharmacological effects such as antiviral [1], antibacterial [2], antifungal [3], antioxidant [4], antiath-erosclerotic [5], and anticancer activities [6].
Mammary CS+SF (ratio NA) 2011 [89] tissue scaffolds impregnated with emodin (antitumor drug) MW and DA not reported Seonwoo et al.
Wu, "Emodin induces apoptosis of human osteosarcoma cells via mitochondria- and endoplasmic reticulum stress-related pathways," International Journal of Clinical and Experimental Pathology, vol.
Hou, "Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats," Journal of Ethnopharmacology, vol.
TCM could produce prominent effects and there are several expert consensuses and recommendations for the treatment of CKD by improving proteinuria, such as Tripterygium and Emodin [69,70].
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