(208) Fluorescence in situ hybridization testing in this manner has been demonstrated to be useful in many of the difficult scenarios that we have previously discussed, including the separation of blue nevi from blue nevus-like metastases, (209) nevoid melanoma from nevi, (210)
desmoplastic melanoma from
desmoplastic nevi, (211) and cellular blue nevi from blue nevus-like melanoma, (212) and in the diagnosis of superficial lesions with suprabasal spread of melanocytes.
The differential diagnosis of this rare entity includes
desmoplastic small round cell tumor (DSRCT), synovial sarcoma, hepatoblastoma and endocrine tumors [4, 6].
Neifeld, "
Desmoplastic Melanoma: Clinical Behavior and Management Implications," Eplasty, vol.
A search of the electronic databases PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and EMBASE for the terms "
desmoplastic" AND "small" AND "round" AND "cell" AND "tumor" was performed.
During the surgery procedure, multiple fragments of both soft and hard tissues were removed; the fragments were sent to the pathology department with a diagnosis of a presumption of recurrent
desmoplastic fibroma.
Microscopically, a nodular well-circumscribed tumor was present in the dermis (Figure 3(a)) and displayed peripheral palisading cells,
desmoplastic changes, and retraction artifact.
A part of the tumor showed a nodular architecture and a
desmoplastic component (Gomori staining).
Serous borderline tumors with invasive implants (as opposed to
desmoplastic implants) and incompletely resected extraovarian implants are associated with increased recurrence and poor prognosis.
Prior research has demonstrated that the
desmoplastic TME of PDAC plays a role in therapeutic resistance, and this study demonstrates that intra-tumoral fibrosis enhances tumor-initiating and self-renewal potential.
While they are classified according to the histopathological variants as follicular, plexiform, acanthomatous and granular cell types, followed by basal cell ameloblastoma,
desmoplastic and clear cell variants, which are the uncommon forms of ameloblastoma according to its histological picture.5 These categories of ameloblastoma are put into different categories on the basis of age when presented site, clinical behaviour and radiographic features and prognosis.6 Peripheral ameloblastoma are formed outside the bone and are slow growing pedunculated or sessile mass with no involvement of the underlying bone and appears on the gingiva and alveolar mucosa and intraosseous ameloblastoma arise in the jaw bone.7
Three types of trichoepithelioma are known; solitary, multiple and the
desmoplastic variety.