The cells then transport the combination to the cell surface so that cytotoxic T cells can have access to them.
Doherty notes that investigators are now using cytotoxic T cells to rid bone marrow transplants of viral infections and are designing vaccines, including those for AIDS, to generate these virus-killing cells.
Factors responsible for this relative resistance to infection and disease include
cytotoxic T cells, neutralizing antibodies, high concentrations of certain chemokines (e.g., RANTES, MIP-1), human leukocyte antigen haplotype, mannose-binding protein, and tumor necrosis factor alpha, C4, and TAP polymorphism (2-4).