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conglutinin

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conglutinin

 [kәn-gloo´tĭ-nin]
a nonimmunoglobulin bovine serum protein that aggregates immune complexes with conglutinogen activity (inactivated C3b) in the presence of divalent cations. It has been used as an indicator system, replacing complement fixation, in serologic tests, and in the detection of immune complexes. Not to be confused with immunoconglutinin.
immune conglutinin immunoconglutinin.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

con·glu·ti·nin

(kon-glū'ti-nin),
Bovine serum protein that, when absorbed by erythrocyte-antibody-complement complexes, causes them to agglutinate; it is comparatively thermostable and apparently dissociates when diluted with physiologic saline solution.
Synonym(s): bovine colloid
Farlex Partner Medical Dictionary © Farlex 2012
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References in periodicals archive
Suzuki et al., "Anti-influenza A virus activities of mannan-binding lectins and bovine conglutinin," Journal of Veterinary Medical Science, vol.
The emerging role of complement lectin pathway in trypanosomatids: molecular bases in activation, genetic deficiencies, susceptibility to infection, and complement system-based therapeutics
The assays that are used routinely in clinical laboratories are based on (a) precipitation of CICs by polyethylene glycol, (b) interaction of CICs with complement (C1q assay), (c) detection of CICs bound to C3 (Raji cell assay, conglutinin assay), and (d) binding of CICs to Fc-recognizing molecules (mRF assay).
Evaluation of seven commercial ELISA kits compared with the C1q solid-phase binding RIA for detection of circulating immune complexes
Unexpected possibilities for the use of conglutinin binding assay in inflammatory rheumatic diseases.
Graphical interpretation of analytical data from comparison of a field method with a reference method by use of difference plots
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