Maurer, "Successful treatment of
cholinergic urticaria with anti-immunoglobulin E therapy," Allergy, vol.
Patients with dermographism and delayed pressure urticaria were more sensitive to omalizumab (13 out of 15 patients showed a complete response) than patients with cold and
cholinergic urticaria (3/6 and 6/8 respectively showed a complete response).
Hydroxyzine is especially effective for the treatment of
cholinergic urticaria. Cyproheptadine (Periactin) is used to treat cold-induced urticaria.
Cholinergic urticaria is tiny, about 1/8 inch bumps surrounded by a white or red halo which come on with exercise, heat or emotion.
researchers' task of identifying the syndrome and its cases, symptoms are difficult to reproduce in laboratory experiments even when victims are challenged with exercise programs identical to those that precipitated episodes, and symptoms are similar to other allergic reactions that occur during exercise like
cholinergic urticaria and exercise-induced asthma.