Butyrylcholinesterase (BChE) is associated with HIV/AIDS progression.
Ingram et al., "Selective
butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer [beta]-amyloid peptide in rodent," Proceedings of the National Academy of Sciences of the United States of America, vol.
An explanation for this finding is caffeine inhibiting the action of
butyrylcholinesterase (BuChe) and acetylcholinesterase enzymes (AChE) (1,6,23).
OPs cause cholinergic syndrome, which may result in death due to inhibition of the enzymes acetyl-cholinesterase (AChE) and
butyrylcholinesterase [(BuChE) or pseudocholinesterase (PChE)].
The isoquinoline alkaloids protopine, allocrytopine and stylopine inhibit human acetylcholinesterase and
butyrylcholinesterase (Cahlikova et al.
Some research groups have developed pharmacological therapies through the use of new drugs, (5,6) others have validated immunotherapy methods based on active and passive vaccination procedures, (7,8) and still others have explored the use of proteins that involve destroying cocaine molecules before they have the chance to pass through the blood-brain barrier and penetrate the nervous tissue (figure 1-B), such as the increase in catalytic activity of enzymes such as
butyrylcholinesterase (BChE)9-11 and hepatic carboxylesterases (hCE-1 and hCE-2).
Acetylcholinesterase,
butyrylcholinesterase, and tyrosinase inhibition studies and antioxidant activities of 33 Scutellaria L.