Multivariate logistic regression revealed that reoperation through a previous incision was independently associated with 2.4-times higher odds of developing an SSI, whereas a prolonged operation (surgery time greater than the 75th percentile), a
blood albumin level of 3.4 mg/dL or less, and COPD each were independently associated with 70%-80% greater odds of developing an SSI.
To test this hypothesis, we measured the albumin concentration in CSF from brain tumor patients and control patients as well as the
blood albumin concentration in brain tumor patients to calculate the CSF/blood albumin ratio, which serves as a good estimate of the integrity of the blood-brain barrier (20).
The system recognizes part of a pattern and asks for the
blood albumin level and gives the pattern: "Low LDL + female + >70 + low
blood albumin = high risk sudden death." It then offers the appropriate peer-reviewed literature and recommended therapies.