Area Postrema Syndrome was diagnosed based on both symptoms and lesions in MRI.
Lesions in the thalamus and pons were more frequent in patients with anti-MOG antibodies, whereas lesions in medulla oblongata and
area postrema were more frequent in patients with anti-AQP4 antibodies.
Autoradiographic analyses confirmed the presence of nesfatin-1 receptors in several brain regions (cerebellum, cortex,
area postrema, dorsal motor nucleus of vagus and hypothalamic paraventricular nucleus), several peripheral organs (kidney, lung, and liver), including the endocrine tissues (adrenal gland, pancreas, pituitary, testis and adipose tissue) (14).
In rabbits, systemic ANGII acts reset arterial baroreflex control of HR to higher pressures through mechanisms involving the
Area Postrema, a brain stem region located near the base of the fourth ventricle (Bishop & Sanderford 2000; Sanderford & Bishop 2002).
Such high incidence of PONV is due to the close proximity of the operating field to the chemoreceptor trigger zone or the
area postrema (vomiting center).
These studies demonstrated that GDNF-family receptor a-like (GFRAL) served as a receptor of GDF15 signalling in the hindbrain (i.e.,
area postrema and nucleus tractus solitarius) which was required for the metabolic effects of GDF15 [9-11].
She was diagnosed with NMO in 2016 after initially presenting with symptoms concerning for
area postrema syndrome, followed by magnetic resonance imaging (MRI) showing a spinal cord lesion from C2-T1 and a positive aquaporin-4 (AQP4) autoantibody.
Vomiting occurs after stimulation of either the vomiting center (VC), a central "control center" in the medulla near the respiratory center, or the chemoreceptor trigger zone (CTZ) in the
area postrema on the floor of the fourth ventricle.