anti-receptor antibody

anti-receptor antibody

Any autoantibody directed against a substrate's receptor, which is capable of altering the cell's response to that substrate. ARAs are pathogenically linked to endocrine disorders, either increased or decreased hormonal activity, and are directed against receptors for corticotropin, H2 (histamine), parathyroid, islet β cells, insulin, thyrotropin (TSH), gastrin and FSH.

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anti-receptor antibody

Immunology A generic term for an autoantibody directed against a substrate's receptor, which is capable of altering the cell's response to that substrate; ARAs are pathogenically linked to endocrine disorders, either ↑ or ↓ hormonal activity, and are directed against receptors for corticotropin, H₂–histamine, parathyroid, islet β cells, insulin, thyrotropin–TSH, gastrin, and FSH. See Autoimmunity.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.