Fibrous pseudotumor is the third most common paratesticular mass, after lipoma and
adenomatoid tumor. It is not a true neoplasm but represents a benign reactive fibrous proliferation resulting from one or several paratesticular elements, more often from the tunica vaginalis (12, 14, 22, 23, 47, 48, 54, 55).
Based on the histopathology and the IHC reactions, the lesion appeared benign and was diagnosed as
adenomatoid tumor with psammoma bodies.
Goodwin, "Nephrogenic metaplasia (
adenomatoid tumors) of bladder," Urology, vol.
Whether it was dentigerous cyst transforming to
adenomatoid tumor or a cystic variant of adenomatoid odontogenic tumor in the present case could not be stated with exactitude as initially to preserve associated tooth only part of cystic lining was removed for histopathological evaluation.
The final diagnosis of
adenomatoid tumor was made (Figure 3).
In the paraffin-embedded (permanent) sections of the mass, the slit-like spaces were thought to be the glandular parts of an
adenomatoid tumor or vascular structures and they stained negative for calretinin and CK7 and positive for CD34.
Markers Useful in the Diagnosis of Paratesticular Tumors (a,b) Antibodies SeCR ReteAC AdT MMeso PSCE PMCE EpAC CK AE1/AE3 + + + + ND ND + EMA - + + -/+ + + + Calret + -/+ + + ND ND +/- WT1 ND - + + ND - + CEA ND -/+ - - + + +/- CD15 - +/- - - + +c +/- ER ND - - - + ND + PAX8 ND + - - + - ND Abbreviations: AdT,
adenomatoid tumor; EpAC, epididymal adenocar -cinoma; MMeso, malignant mesothelioma; PMCE, papillary mucinous cystadenoma of epididymis; PSCE, papillary serous cystadenoma of epididymis; ReteAC, adenocarcinoma of rete testis; SeCR, sertoliform cystadenoma of rete testis.
Adenomatoid tumor of the bladder reproducing renal structures (nefrogenic adenoma).
The adenomatoid odontogenic tumor, ameloblastic
adenomatoid tumor or adenoameloblastoma.
The differential diagnosis includes malignant testicular tumor,
adenomatoid tumor, epididymitis, hemangioma and hematoma.