dac·ti·no·my·cin
(dak'ti-nō-mī'sin), An antineoplastic antibiotic produced by several species of
Streptomyces (for example,
S. parvulus).
See also:
actinomycins.
Farlex Partner Medical Dictionary © Farlex 2012
actinomycin D
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Actinomycin D
A relatively toxic antibiotic produced by Streptomyces spp, which is used as a chemotherapeutic.
Mechanism Inhibits DNA transcription by RNA polymerase.
Indications Rhabdomyosarcoma, Wilms’ tumour, gestational trophoblastic tumour
Adverse effects Anorexia, nausea, vomiting, myelosuppression with pancytopenia, diarrhoeaSegen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
actinomycin D
Cosmegen®, dactinomycin Oncology A relatively toxic antibiotic produced by Streptomyces spp, used as a chemotherapeutic Mechanism Inhibits DNA transcription by RNA polymerase Indications Rhabdomyosarcoma, Wilms' tumor Adverse effects Anorexia, N&V, myelosuppression with pancytopenia, diarrheaMcGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
actinomycin D
Dactinomycin, an antibiotic derived from Streptomyces pavullus which causes breaks in DNA. This side effect renders it unsuitable as an antibacterial drug, but makes it useful as an anti-cancer drug. A brand name is Cosmegen Lyovac. There are other actinomycins in the group produced by Streptomyces chrysomallas .Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
actinomycin D
a substance that inhibits the transcription of RNA from DNA. When isolated from soil bacteria and used pharmaceutically it acts as an ANTIBIOTIC.Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005