a·ce·tyl-CoA ac·yl·trans·fer·ase

an enzyme catalyzing the thioclastic cleavage by coenzyme A of β-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation.
See also: acetyl-CoA acetyltransferase.

Synonym(s): 3-ketoacyl-CoA thiolase, β-ketothiolase

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References in periodicals archive

Primer sequences for acetyl-CoA acyltransferase (ACAA2), long-chain acyl-CoA dehydrogenase (ACADL), acyl-CoA synthetase (ACSL1), very long chain acyl-CoA dehydrogenase (ACADVL), carnitine palmitoyltransferase 1B (CPT1B), enoyl-CoA hydratase (ECH1), hydroxyacyl-CoA dehydrogenase (HADHA), pyruvate dehydrogenase kinase (PDK4), PGC-1[alpha], PGC-1[beta], PPAR[alpha], glutamate dehydrogenase, and 18S ribosomal RNA are available in Supplemental Material, Table S1 (http://dx.doi.org/10.1289/ehp.1205056).

Phthalate exposure changes the metabolic profile of cardiac muscle cells

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