Weber-Christian disease

[va´ber kris´chan]

a disease marked by fever and the formation of crops of tender nodules in the subcutaneous fatty tissues. Called also nodular nonsuppurative panniculitis and Christian-Weber disease.

Web·er-Chris·tian dis·ease

(vā'bĕr kris'chĕn),

relapsing febrile nodular nonsuppurative panniculitis of undetermined cause.Synonym(s): relapsing febrile nodular nonsuppurative panniculitis

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Weber-Christian syndrome

A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion.

Clinical findings
Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis.

Lab
Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia.

DiffDx
Erythema induratum, sarcoidosis, post-injection fat necrosis.

Management
Symptomatic relief with corticosteroids, chloroquine, phenylbutazone.

re·lap·sing fe·brile nod·u·lar non·sup·pur·a·tive pan·ni·cu·li·tis

(rē-lap'sing feb'ril nod'yū-lăr non'sŭp'yŭr-ă-tiv pă-nik'yū-lī'tis)

Nodular fat necrosis of a varietyof possible causes.
Synonym(s): Christian disease (2) , Christian syndrome, Weber-Christian disease.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Christian,

Henry Asbury, U.S. internist, 1876-1951.

Christian disease - (1) Synonym(s): Hand-Schüller-Christian disease; - ; (2) Synonym(s): Weber-Christian disease

Christian syndrome - Synonym(s): Hand-Schüller-Christian disease

Hand-Schüller-Christian disease - see under Hand

Weber-Christian disease - see under Weber, Frederick Parkes

Weber,

Frederick Parkes, English physician, 1863-1962.

Klippel-Trenaunay-Weber syndrome - see under Klippel

Rendu-Osler-Weber syndrome - see under Rendu

Sturge-Kalischer-Weber syndrome - Synonym(s): Sturge-Weber syndrome

Sturge-Weber disease - Synonym(s): Sturge-Weber syndrome

Sturge-Weber syndrome - see under Sturge

Weber-Christian disease - a group of conditions with recurrent subcutaneous nodules, with or without fever or suppuration, followed by depression of the overlying skin. Synonym(s): Christian disease (2); nodular nonsuppurative panniculitis

Weber-Cockayne syndrome - epidermolysis bullosa of the hands and feet.